Mammalian embryogenesis is the process of cell division and cellular differentiation during early prenatal development which leads to the development of a mammalian embryo.
Embryogenesis
Due to the fact that placental mammals and marsupials nourish their developing embryos via the placenta, the ovum in these species does not contain significant amounts of yolk, and the yolk sac in the embryo is relatively small in size, in comparison with both the size of the embryo itself and the size of yolk sac in embryos of comparable developmental age from lower chordates. The fact that an embryo in both placental mammals and marsupials undergoes the process of implantation, and forms the chorion with its chorionic villi, and later the placenta and umbilical cord, is also a difference from lower chordates.
The difference between a mammalian embryo and an embryo of a lower chordate animal is evident starting from blastula stage. Due to that fact, the developing mammalian embryo at this stage is called a blastocyst, not a blastula, which is more generic term.
There are also several other differences from embryogenesis in lower chordates. One such difference is that in mammalian embryos development of the central nervous system and especially the brain tends to begin at earlier stages of embryonic development and to yield more structurally advanced brain at each stage, in comparison with lower chordates. The evolutionary reason for such a change likely was that the advanced and structurally complex brain, characteristic of mammals, requires more time to develop, but the maximum time spent in utero is limited by other factors, such as relative size of the final fetus to the mother (ability of the fetus to pass mother's genital tract to be born), limited resources for the mother to nourish herself and her fetus, etc. Thus, to develop such a complex and advanced brain in the end, the mammalian embryo needed to start this process earlier and to perform it faster.
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During development, cell fates are governed by multiple microenvironmental cues and their integration by specific signal transduction pathways. This course focuses on imaging of mechanosensory cilia o
The blastocyst is a structure formed in the early embryonic development of mammals. It possesses an inner cell mass (ICM) also known as the embryoblast which subsequently forms the embryo, and an outer layer of trophoblast cells called the trophectoderm. This layer surrounds the inner cell mass and a fluid-filled cavity known as the blastocoel. In the late blastocyst the trophectoderm is known as the trophoblast. The trophoblast gives rise to the chorion and amnion, the two fetal membranes that surround the embryo.
Mammalian development begins with the segregation of embryonic and extra-embryonic lineages in the blastocyst. Recent studies revealed cell-to-cell gene expression heterogeneity and dynamic cell rearrangements during mouse blastocyst formation. Thus, mecha ...
BACKGROUND: Acquisition of lineage-specific cell cycle duration is a central feature of metazoan development. The mechanisms by which this is achieved during early embryogenesis are poorly understood. In the nematode Caenorhabditis elegans, differential ce ...
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The resolving power, chemical sensitivity and non-invasive nature of NMR have made it an established technique for in vivo studies of large organisms both for research and clinical applications. NMR would clearly be beneficial for analysis of entities at t ...