A stenosis (from Ancient Greek στενός, "narrow") is an abnormal narrowing in a blood vessel or other tubular organ or structure such as foramina and canals. It is also sometimes called a stricture (as in urethral stricture).
Stricture as a term is usually used when narrowing is caused by contraction of smooth muscle (e.g. achalasia, prinzmetal angina); stenosis is usually used when narrowing is caused by lesion that reduces the space of lumen (e.g. atherosclerosis). The term coarctation is another synonym, but is commonly used only in the context of aortic coarctation.
Restenosis is the recurrence of stenosis after a procedure.
The resulting syndrome depends on the structure affected.
Examples of vascular stenotic lesions include:
Intermittent claudication (peripheral artery stenosis)
Angina (coronary artery stenosis)
Carotid artery stenosis which predispose to (strokes and transient ischaemic episodes)
Renal artery stenosis
The types of stenoses in heart valves are:
Pulmonary valve stenosis, which is the thickening of the pulmonary valve, therefore causing narrowing
Mitral valve stenosis, which is the thickening of the mitral valve (of the left heart), therefore causing narrowing
Tricuspid valve stenosis, which is the thickening of the tricuspid valve (of the right heart), therefore causing narrowing
Aortic valve stenosis, which is the thickening of the aortic valve, therefore causing narrowing
Stenoses/strictures of other bodily structures/organs include:
Pyloric stenosis (gastric outflow obstruction)
Lumbar, cervical or thoracic spinal stenosis
Subglottic stenosis (SGS)
Tracheal stenosis
Obstructive jaundice (biliary tract stenosis)
Bowel obstruction
Phimosis
Non-communicating hydrocephalus due to aqueductal stenosis
Stenosing tenosynovitis
Atherosclerosis
Esophageal stricture
Achalasia
Prinzmetal angina
Vaginal stenosis
Meatal stenosis
alcohol
atherosclerosis causes stenotic lesions in arteries.
birth defects
calcification
diabetes
headbanging – as in the case of Dave Mustaine
iatrogenic, e.g.
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This lecture will cover anatomy and physiology of the cardiovascular system, biophysics of the blood, cardiac mechanics, hemodynamics and biomechanics of the arterial system, microcirculation and biom
The transaortic valvular pressure gradient (TPG) plays a central role in decision-making for patients suffering from severe aortic stenosis. However, the flow-dependence nature of the TPG makes the diagnosis of aortic stenosis challenging since the markers ...
MDPI2023
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IntroductionArterial wave reflection is an important component of the left ventricular afterload, affecting both pressure and flow to the aorta. The aim of the present study was to evaluate the impact of wave reflection on transvalvular pressure gradients ...
FRONTIERS MEDIA SA2022
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Introduction: Pulmonary hypertension (PH), traditionally defined as a mean pulmonary artery pressure (PAP) >= 25 mmHg, is associated with poor outcomes in patients undergoing a transcatheter aortic valve replacement (TAVR) for severe aortic stenosis (AS). ...