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Correlation of photodynamic activity (PDT) and fluorescence signaling for free and pegylated meta-tetrahydroxyphenylchlorin (mTHPC) in nude mice with mesothelioma xenografts. ...
We report a comprehensive in vitro study of the photo-oxidative stress on different biomolecular and cellular targets generated in the presence of fullerol C-60(OH)(n), a novel, fullerene-based and water-soluble sensitizer of singlet oxygen ((1)Delta(g)). ...
Photodynamic therapy (PDT) may modify the mucosal immune response and thus serve as a therapy for Crohn’s disease (CD). After evaluating safety in BALB/c mice and establishing an endoscopic index of colitis (EIC), we could demonstrate that a single «low do ...
The formation and quenching of the triplet state of xanthone are studied by femtosecond techniques. As revealed by femtosecond fluorescence spectroscopy, the primarily excited 1ππ* state decays within 1.5 ps. In a transient absorption experiment, this time ...
Carbonate radical (CO3-) is a powerful oxidant that is present in sunlit surface waters and in waters treated by advanced oxidation processes. The production of CO3- in aqueous solution through oxidation of carbonate anion by excited triplet states of arom ...
This invention relates to oligonucleotide targeting agents and their use in the treatment of diseased cells by selective photochemotherapy (PCT). PCT is a method of treating human diseases and disorders, bacteriological indications and other pathological c ...
To explore how baseline lesion composition influenced vision outcomes in patients with age-related macular degeneration (AMD) undergoing photodynamic therapy with verteporfin (Visudyne) for subfoveal choroidal neovascularization (CNV) in the Treatment of A ...
Efficacy and tumour selectivity of photodynamic therapy with two clinically approved sensitizers (mTHPC, verteporfin) were assessed for focal intracavitary photodynamic therapy (PDT) in rodents with malignant pleural mesothelioma (MPM) at recommended drug- ...
Crohn's disease is an inflammatory bowel disease originating from an overwhelming response of the mucosal immune system. Low dose photodynamic therapy (PDT) may modify the mucosal immune response and thus serve as a therapy for Crohn's disease. Most patien ...