Category
Pulmonology
Related publications (256)
How to Count Coughs: An Event-Based Framework for Evaluating Automatic Cough Detection Algorithm Performance
David Atienza Alonso, Tomas Teijeiro Campo, Lara Orlandic, Jonathan Dan, Jérôme Paul Rémy Thevenot
Chronic cough disorders are widespread and challenging to assess because they rely on subjective patient questionnaires about cough frequency. Wearable devices running Machine Learning (ML) algorithms are promising for quantifying daily coughs, providing c ...
arXiv2024Inhalation of Microplastics—A Toxicological Complexity
Florian Frédéric Vincent Breider, Myriam Borgatta
Humans are chronically exposed to airborne microplastics (MPs) by inhalation. Various types of polymer particles have been detected in lung samples, which could pose a threat to human health. Inhalation toxicological studies are crucial for assessing the e ...
2024Inactivation of influenza A virus in expiratory droplets and aerosol particles and the associated physicochemical drivers
Influenza is an infectious respiratory illness caused by influenza viruses. Every year, it causes up to one billion cases of disease worldwide. Despite its high disease burden, the transmission pathway of influenza remains subject to debate. There is incre ...
EPFL2024Stability of influenza A virus in droplets and aerosols is heightened by the presence of commensal respiratory bacteria
Athanasios Nenes, Tamar Kohn, Kalliopi Violaki, Ghislain Gilles Jean-Michel Motos, Aline Laetitia Schaub, Shannon Christa David, Walter Hugentobler, Htet Kyi Wynn, Céline Terrettaz, Laura José Costa Henriques, Daniel Scott Nolan, Marta Augugliaro
Aerosol transmission remains a major challenge for control of respiratory viruses, particularly those causing recurrent epidemics, like influenza A virus (IAV). These viruses are rarely expelled alone, but instead are embedded in a consortium of microorgan ...
2024Human alveolar lining fl uid from the elderly promotes Mycobacterium tuberculosis intracellular growth and translocation into the cytosol of alveolar epithelial cells
Vivek Vijay Thacker, Richa Mishra
The elderly population is highly susceptible to developing respiratory diseases, including tuberculosis, a devastating disease caused by the airborne pathogen Mycobacterium tuberculosis ( M.tb ) that kills one person every 18 seconds. Once M.tb reaches the ...
Elsevier Science Inc2024Single-cell analysis of the interactions between Mycobacterium tuberculosis and macrophages
Mycobacterium Tuberculosis is a highly effective pathogen infecting nearly a third of the world's population. An M. tuberculosis infection starts when droplets containing bacteria enter an individual's lungs. The first host cells to contact the bacteria ar ...
EPFL2024Compliant vascular grafts and methods of use
Nikolaos Stergiopoulos, Georgios Rovas
Compliant vascular grafts for implantation in the vasculature are provided. The compliant vascular grafts are designed to expand longitudinally and radially within a blood vessel, such as an artery, and is expected to be particularly well suited for treati ...
2024The neuraminidase activity of influenza A virus determines the strain-specific sensitivity to neutralization by respiratory mucus
Athanasios Nenes, Tamar Kohn, Kalliopi Violaki, Ghislain Gilles Jean-Michel Motos, Aline Laetitia Schaub, Shannon Christa David, Walter Hugentobler
Respiratory mucus lining the airway epithelium constitutes an important first line of defense against infection with influenza A virus (IAV). Previous studies suggested that the inhibitory potential of mucus relies not only on the presence of decoy recepto ...
2023Deep learning parametric response mapping from inspiratory chest CT scans: a new approach for small airway disease screening
Jiancheng Yang, Zhiye Wang, Jun Lu, Zhigang Li, Lin Qi, Ming Li, Bo Du, Yuxuan Sun, Ziyi Liu
Objectives Parametric response mapping (PRM) enables the evaluation of small airway disease (SAD) at the voxel level, but requires both inspiratory and expiratory chest CT scans. We hypothesize that deep learning PRM from inspiratory chest CT scans can eff ...
London2023DeepBreath-automated detection of respiratory pathology from lung auscultation in 572 pediatric outpatients across 5 countries
Martin Jaggi, Mary-Anne Hartley, Juliane Dervaux, Tatjana Chavdarova, Daniel Mueller, Julien Niklas Heitmann, Daniel Hinjos García
The interpretation of lung auscultation is highly subjective and relies on non-specific nomenclature. Computer-aided analysis has the potential to better standardize and automate evaluation. We used 35.9 hours of auscultation audio from 572 pediatric outpa ...
NATURE PORTFOLIO2023