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Hv1 is a transmembrane four-helix bundle that transports protons in a voltage-controlled manner. Its crucial role in many pathological conditions, including cancer and ischemic brain damage, makes Hv1 a promising drug target. Starting from the recently sol ...
Amorphous silica-based nanotubes (SBNTs) were synthesized from phosphoryl triamide, OP(NH2)(3), thiophosphoryl triamide, SP(NH2)(3), and silicon tetrachloride, SiCl4, at different temperatures and with varying amount of the starting material SiCl4 using a ...
Our recently solved high-resolution structure of the serotonin 5-HT3 receptor (5-HT3R) delivered the first detailed structural insights for a mammalian pentameric ligand-gated ion channel. Based on this structure, we here performed a total of 2.8-μs all-at ...
TLS 1.3 takes important steps to improve both performance and security, so far offers little protection against traffic analysis or fingerprinting using unencrypted metadata or other side-channels such as transmission lengths and timings. This paper explor ...
Erosion shapes our landscape and occurs when a sufficient shear stress is exerted by a fluid on a sedimented layer. What controls erosion at a microscopic level remains debated, especially near the threshold forcing where it stops. Here we study, experimen ...
Emergent behaviour from electron-transport properties is routinely observed in systems with dimensions approaching the nanoscale(1). However, analogous mesoscopic behaviour resulting from ionic transport has so far not been observed, most probably because ...
Understanding the structure and dynamics of water's constituent ions, proton and hydroxide, has been a subject of numerous experimental and theoretical studies over the last century. Besides their obvious importance in acid-base chemistry, these ions play ...
This paper studies the possibility of adding an experimental channel into the core of the CROCUS nuclear reactor. Thinking about all the implications of the installation of a channel, different configurations for the insertion of a channel are discussed. T ...
The lack of knowledge regarding air entrainment caused by large jets in hydraulic structures, such as downstream Pelton turbines, has led EDF (Electricité de France) to carry out a test series to optimize the La Coche Power plant. The data extracted from t ...
The coupling between open channel-based microchip electrophoresis and mass spectrometry via electrostatic spray ionization is proposed for in situ detection of fractionated analytes. Electrophoretic separation is performed in an open channel fabricated in ...