Concept

Hydrophobic effect

Related publications (94)

NMR diffusion and relaxation studies of the encapsulation of fragrances by amphiphilic multiarm star block copolymers

Harm-Anton Klok, John Christopher Plummer, Céline Ternat

Self-diffusion NMR spectroscopy and relaxometry have been employed to study fragrance encapsulation in water-soluble, amphiphilic star block copolymers. Diffusion coefficients of four different fragrance molecules in the free form and in the presence of th ...

2007

Selective deposition of gold nanoparticles using Van der Waals interactions

Jürgen Brugger, Marc Antonius Friedrich van den Boogaart

Gold nanoparticles with hydrophobic surface have been deposited on a silicon substrate chemically patterned by reactive ion etching through a stencil mask and chemical vapour deposition of alkyl silanes. After deposition by dipping and adequate rinsing, th ...

2007

Photoinduced Bimolecular Electron Transfer Investigated by Femtosecond Time-Resolved Infrared Spectroscopy

Natalie Renuka Banerji, Eric Vauthey

Ultrafast infrared transient absorption spectroscopy is used to study the photoinduced bimolecular electron transfer reaction between perylene in the first singlet excited state and 1,4-dicyanobenzene in acetonitrile and dichloromethane. Following vibratio ...

2006

Design and synthesis of macrocycles active against vancomycin-resistant enterococci (VRE): the interplay between D-Ala-D-Lac binding and hydrophobic effect

Jieping Zhu

A modified vancomycin binding pocket (D-O-E ring) incorporating a CHNHCOR function at the AA4 position is designed and synthesized. Potent bioactivities against both sensitive- and resistant-strain are found for some of these compds. (MIC 4 micro g/mL agai ...

2005

Effective interactions between chaotropic agents and proteins

Paolo De Los Rios

Chaotropic agents are cosolutes that can disrupt the hydrogen bonding network between water molecules and reduce the stability of the native state of proteins by weakening the hydrophobic effect. In this work, we represent the chaotropic agent as a factor ...

2005

Development of a novel drug delivery system based on polymeric, thermoresponsive, hydrogel nanoparticles

Carrier-mediated drug delivery has emerged as a powerful methodology for the treatment of various pathologies. The therapeutic index of traditional and novel drugs is enhanced via the increase of specificity due to targeting of drugs to a particular tissue ...

EPFL2005

Structural basis for the cytoskeletal association of Bcr-Abl/c-Abl

Oliver Hantschel

The Bcr-Abl tyrosine kinase causes different forms of leukemia in humans. Depending on its position within the cell, Bcr-Abl differentially affects cellular growth. However, no structural and molecular details for the anticipated localization determinants ...

Elsevier2005

Tunable surface nanostructures from Block copolymer self-assembly

Jürgen Brugger, Sivashankar Krishnamoorthy, Harry Heinzelmann, Raphaël Pugin

Nanostructures are known to exhibit novel optical, electrical, and magnetic and many other interesting physical properties and a lot of research has been invested on the synthesis and study of such structures in the recent years. The massive drive towards ...

2005

Polyphenylene dendrimers as scaffolds for shape-persistent multiple peptide conjugates

Harm-Anton Klok

The present work describes synthetic concepts for the coupling of peptides to polyphenylene dendrimers (PPDs). Novel functionalized cyclopentadienones have been synthesized whose Diels-Alder cycloaddition with various core molecules leads to polyphenylene ...

2005

Thermodynamics of Binding of 2-Methoxy-3-isopropylpyrazine and 2-Methoxy-3-isobutylpyrazine to the Major Urinary Protein

Geoffrey Bodenhausen, Chiara Perazzolo

In the present study the authors examine the thermodn. of binding of two related pyrazine-derived ligands to the major urinary protein, MUP-I, using a combination of isothermal titrn. calorimetry (ITC), x-ray crystallog., and NMR backbone 15N and Me side-c ...

2004

Graph Chatbot

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.