Concept

Preventive healthcare

Related publications (50)

A Tunable Self-Offloading Module for Plantar Pressure Regulation in Diabetic Patients

Yves Perriard, Yoan René Cyrille Civet, Paolo Germano, Christian Köchli, Sofia Lydia Ntella, Kenny Jeanmonod, Bhawnath Tiwari

Plantar pressure plays a crucial role in the pathogenesis of foot ulcers among patients with diabetes and peripheral polyneuropathy. Pressure relief is a key requirement for both the prevention and treatment of plantar ulcers. Conventional medical practice ...

2024

Spatial analysis of 10-year predicted risk and incident atherosclerotic cardiovascular disease: the CoLaus cohort

Stéphane Joost, Idris Guessous, David Nicolas De Ridder, Guillaume Jordan

Whether cardiovascular risk scores geographically aggregate and inform on spatial development of atherosclerotic cardiovascular diseases (ASCVD) remains unknown. Our aim is to determine the spatial distribution of 10-year predicted cardiovascular risk and ...

2024

Broadly potent anti-SARS-CoV-2 antibody shares 93% of epitope with ACE2 and provides full protection in monkeys

Didier Trono, Henning Paul-Julius Stahlberg, Priscilla Turelli, Florence Pojer, Charlène Mireille Raymonde Raclot, Kelvin Ka Ching Lau, Myriam Isabelle Lamrayah, Jérémy Campos, Vanessa Genet

Due to the rapid evolution of SARS-CoV-2 to variants with reduced sensitivity to vaccine-induced humoral immunity and the near complete loss of protective efficacy of licensed therapeutic monoclonal antibodies, we isolated a potent, broad-spectrum neutrali ...

2023

Different health systems-Different mortality outcomes? Regional disparities in avoidable mortality across German-speaking Europe, 1992-2019

Mathias Lerch

Background: Evaluating the impact of health systems on premature mortality across different countries is a very challenging task, as it is hardly possible to disentangle it from the influence of contextual factors such as cultural differences. In this resp ...

PERGAMON-ELSEVIER SCIENCE LTD2023

Mechanism of KRAS-driven T cell infiltration in colorectal cancer

Amber Dawn Bowler

Colorectal cancer is the second-leading cause of cancer death worldwide. Early-stage disease can be detected with preventative medical screening and is treatable with surgical resection. Sixty-percent of patients, however, are diagnosed with advanced-stage ...

EPFL2023

Emerging Threats of Synthetic Biology and Biotechnology. Addressing Security and Resilience Issues

Synthetic biology is a field of biotechnology that is rapidly growing in various applications, such as in medicine, environmental sustainability, and energy production. However these technologies also have unforeseen risks and applications to humans and th ...

Springer2021

Novel broad-spectrum virucidal antivirals

Matteo Gasbarri

The current COVID-19 pandemic has showed the threats that viruses can cause to the whole world. Over 200 million infections and over 4.5 million deaths and enormous socio-economic impact were the output of the emergence of a single new pathogen: SARS-CoV-2 ...

EPFL2021

Geospatial Analysis of Sodium and Potassium Intake: A Swiss Population-Based Study

Stéphane Joost, Idris Guessous, Murielle Bochud, David Nicolas De Ridder

Inadequate sodium and potassium dietary intakes are associated with major, yet preventable, health consequences. Local public health interventions can be facilitated and informed by fine-scale geospatial analyses. In this study, we assess the existence of ...

MDPI2021

Toward Nanotechnology-Enabled Approaches against the COVID-19 Pandemic

Francesco Stellacci

The COVID-19 outbreak has fueled a global demand for effective diagnosis and treatment as well as mitigation of the spread of infection, all through large-scale approaches such as specific alternative antiviral methods and classical disinfection protocols. ...

AMER CHEMICAL SOC2020

Patient‐specific logic models of signaling pathways from screenings on cancer biopsies to prioritize personalized combination therapies

Christoph Merten

Mechanistic modeling of signaling pathways mediating patient-specific response to therapy can help to unveil resistance mecha-nisms and improve therapeutic strategies. Yet, creating suchmodels for patients, in particular for solid malignancies, is chal-len ...

2020

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