Related publications (69)

Sampling and reconstructing spatial fields using mobile sensors

Martin Vetterli, Jayakrishnan Unnikrishnan

The classical approach to sampling time-invariant spatial fields uses static sensors distributed over space. We study a new approach involving mobile sensors that move through space measuring the field values along their paths. A single moving sensor can t ...
Ieee2012

Discovery of a novel aggregation domain in the huntingtin protein: implications for the mechanisms of Htt aggregation and toxicity

Hilal Lashuel

Aggravating aggregation: an N-terminal domain that is in close proximity to the polyQ domain in the huntingtin protein, htt105-138, is shown to be highly aggregation prone. Potential cross-talk between this domain and the polyQ region may play a central ro ...
Wiley-Blackwell2012

Does the apple always fall close to the tree? The geographical proximity choice of spinouts

Christopher Tucci, Andrew King

Previous studies suggest that spin-outs will locate in close proximity to the firm from which the), spawn. As a result of this process, clusters of entrepreneurial activity tend to develop around a few strong parent firms. But do all spin-outs really stay ...
2011

Extreme temperature analysis under forest cover compared to an open field

Anthony Christopher Davison, Martine Rebetez, Jacques Ferrez

We analyse air temperature data from 14 sites in Switzerland, each with two weather stations in close proximity, one under a forest canopy and the other in the open. We use the statistics of extremes to investigate how extremely high maximum and extremely ...
2011

Phosphorylation of alpha-Synuclein at Y125 and S129 Alters Its Metal Binding Properties: Implications for Understanding the Role of alpha-Synuclein in the Pathogenesis of Parkinson's Disease and Related Disorders

Hubert Girault, Hilal Lashuel, Michel Prudent, Bruno Claude Daniel Fauvet, Yu Lu

alpha-Synuclein (alpha-syn) is a 140-amino acid protein that plays a central role in the pathogenesis of Parkinson's disease (PD) and other synucleinopathies. However, the molecular determinants that are responsible for triggering and/or propagating alpha- ...
American Chemical Society2011

Structural Insights into the Specificity of Xyn10B from Paenibacillus barcinonensis and Its Improved Stability by Forced Protein Evolution

Pierre Vogel

Paenibacillus barcinonensis is a soil bacterium bearing a complex set of enzymes for xylan degradation, including several secreted enzymes and Xyn10B, one of the few intracellular xylanases reported to date. The crystal structure of Xyn10B has been determi ...
2010

Microfluidic Protein Preconcentrator Using a Microchannel-Integrated Nafion Strip: Experiment and Modeling

Martinus Gijs, Venkataragavalu Sivagnanam, Meng Shen

We propose a simple microfluidic device for protein preconcentration based on the electrokinetic trapping principle. It comprises a narrow Nafion strip that is simply cut from a commercial membrane and is integrated into a molded poly(dimethylsiloxane) (PD ...
American Chemical Society2010

Methane- and ammonia-oxidizing bacteria at the chemocline of Lake Kinneret (Israel)

The vertical distribution of methane- and ammonia-oxidizing bacteria (MOB and AOB, respectively), and the physicochemical conditions in the chemocline of Lake Kinneret (Israel) were studied at a resolution of 10 cm from 16.2 to 17.7 m depth. Profiles of th ...
2010

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