Concept

Fat

Related publications (85)

Muscle or liver-specific Sirt3 deficiency induces hyperacetylation of mitochondrial proteins without affecting global metabolic homeostasis

Johan Auwerx, Kristina Schoonjans, Carlos Canto Alvarez, Pénélope Andreux, Norman Lionel Moullan, Eija Riitta Pirinen, Hiroyasu Yamamoto, Taoufiq Harach, Pablo Jose Fernandez Marcos, Ellen Helena Jeninga

Sirt3 is a mitochondrial sirtuin, predominantly expressed in highly metabolic tissues. Germline ablation of Sirt3 has major metabolic consequences, including increased susceptibility to metabolic damage and oxidative stress after high fat feeding. In order ...

2012

Who said fat is bad? Skull-stripping benefits from additional fat image

Tobias Kober, Reto Meuli

Being a preliminary step for many clinical applications and analyses, accurate skull-stripping is a key challenge in MR brain imaging. One of its major difficulties arises from the contrast similarities at brain/non-brain tissue interfaces, in particular b ...

2011

Dermal collagen and lipid deposition correlate with tissue swelling and hydraulic conductivity in murine primary lymphedema

Melody Swartz, Joseph Rutkowski

Primary lymphedema is a congenital pathology of dysfunctional lymphatic drainage characterized by swelling of the limbs, thickening of the dermis, and fluid and lipid accumulation in the underlying tissue. Two mouse models of primary lymphedema, the Chy mo ...

American Society for Investigative Pathology2010

Influence of emulsion composition on lubrication capacity and texture perception

Stefano Mischler

P>The role of fat content and type of surfactant for oral friction processes and texture perception of oil-in-water emulsions was assessed. Emulsions at 22% and 33% fat content containing either sodium caseinate or a sucrose ester as emulsifier were compar ...

2009

mTOR complex 2 in adipose tissue negatively controls whole- body growth

Johan Auwerx

Mammalian target of rapamycin (mTOR), a highly conserved protein kinase that controls cell growth and metabolism in response to nutrients and growth factors, is found in 2 structurally and functionally distinct multiprotein complexes termed mTOR complex 1 ...

2009

Advanced hydro-mechanical coupling for unified constitutive modelling of unsaturated soils

Lyesse Laloui, Mathieu Nuth

A new unified constitutive hydro-mechanical model named ACMEG-s is formulated to improve modelling of unsaturated soils in free or constrained conditions. Indeed, due to particular mechanical and hydraulic boundary conditions, some natural and engineered f ...

Taylor & Francis2008

Advanced hydro-mechanical coupling for unified constitutive modelling of unsaturated soils

Lyesse Laloui, Mathieu Nuth

Crc Press-Taylor & Francis Group, 6000 Broken Sound Parkway Nw, Ste 300, Boca Raton, Fl 33487-2742 Usa2008

LRP1 controls intracellular cholesterol storage and fatty acid synthesis through modulation of Wnt signaling

Johan Auwerx, Lei Zhou

The low-density lipoprotein receptor-related protein LRP1 is a cell surface receptor with functions in diverse physiological pathways, including lipid metabolism. Here we show that LRP1-deficient fibroblasts accumulate high levels of intracellular choleste ...

2008

Specific SIRT1 activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation

Johan Auwerx, Carlos Canto Alvarez, Chikage Mataki

The NAD(+)-dependent deacetylase SIRT1 controls metabolic processes in response to low nutrient availability. We report the metabolic phenotype of mice treated with SRT1720, a specific and potent synthetic activator of SIRT1 that is devoid of direct action ...

2008

Biodegradation and environmental behavior of biodiesel mixtures in the sea: An initial study

Jeremy Samuel Arey

Biodiesel, a mixture of fatty acid methyl esters (FAMEs) derived from animal fats or vegetable oils, is rapidly moving towards the mainstream as an alternative source of energy. However, the behavior of biodiesel, or blends of biodiesel with fossil diesel, ...

Elsevier2007

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