Publications related to Biosynthesis

Corrinoid auxotrophy in the obligate organohalide respiring Dehalobacter restrictus

Christof Holliger, Julien Maillard, Aamani Rupakula Boyanapalli, Kiyan Shabestary

Background Corrinoids are an essential cofactor of reductive dehalogenases, the key enzymes of the environmental-friendly process of organohalide respiration (OHR). Dehalobacter restrictus strain PER-K23 is an obligate OHR bacterium (OHRB) able to conserve ...

2013

Diversity of cobalamin riboswitches in the corrinoid-producing organohalide respirer Desulfitobacterium hafniense

Christof Holliger, Julien Maillard, Emmanuelle Rohrbach, Aurélie Duret

The strategic adaptation of prokaryotes in polluted niches involves the efficient regulation of their metabolism. The obligate anaerobe and metabolically versatile Desulfitobacterium hafniense reductively dechlorinates halogenated organic compounds (so-cal ...

Amer Soc Microbiology2013

Catalytic Friedel-Crafts Reaction of Aminocyclopropanes

Jérôme Waser, Florian Patrick Marie Daniel De la Barre De Nanteuil, Joachim Loup

A Lewis acid catalyzed Friedel-Crafts reaction between donor-acceptor aminocyclopropanes and indoles and other electron-rich aromatic compounds is reported. Indole alkylation at the C3 position was generally obtained for a broad range of functional groups ...

American Chemical Society2013

Photodynamics of Lys+-Trp Protein Motifs: Hydrogen Bonds Ensure Photostability

Ursula Röthlisberger, Ivano Tavernelli, Matteo Guglielmi

Cation-pi interactions such as Lys(+)-Trp, are highly abundant structural motifs in proteins. Both, experimental and theoretical studies of small prototypical gas phase systems, H(+)Trp, H(+)Trp center dot(H2O)(n) and H+ Gly-Trp, indicate such an arrangeme ...

Royal Soc Chemistry2013

On-the-Fly Kinetics of Enzymatic Racemization Using Deuterium NMR in DNA-Based Chiral Oriented Media

Geoffrey Bodenhausen

We report the in situ and real-time monitoring of the interconversion of L- and D-alanine-d(3) by alanine racemase from Bacillus stearothermophilus directly observed by H-2 NMR spectroscopy in anisotropic phase. The enantiomers are distinguished by the dif ...

American Chemical Society2013

Nafion (R)/histidine functionalized carbon nanotube: High-performance fuel cell membranes

Mohammad Mahdi Hasani-Sadrabadi

Here we show preparation and characterization of a new type of composite membrane based on Nafion (R)/histidine modified carbon nanotube by imidazole groups (Im-CNT), for direct methanol fuel cell (DMFC) applications. Due to the presence of this imidazole- ...

Pergamon-Elsevier Science Ltd2013

Kinetic modeling of the yeast sphingolipid metabolism identifies prevalent mutant strains through integration of lipidomic data profiles

Vassily Hatzimanikatis, Paolo Angelino, Howard Riezman, Georgios Savoglidis

Sphingolipids are abundant components of eukaryotic cells. Their localization in the plasma membrane allows for the cell to carry out multiple important functions for its viability. One of the most important roles of the sphingolipids is their ability to f ...

2012

Structural Basis for Benzothiazinone-Mediated Killing of Mycobacterium tuberculosis

Paul Joseph Dyson, Stewart Cole, John McKinney, Neeraj Dhar, Florence Pojer, Joao Pedro De Almeida Neres, Elizabeth Fullam

The benzothiazinone BTZ043 is a tuberculosis drug candidate with nanomolar whole-cell activity. BTZ043 targets the DprE1 catalytic component of the essential enzyme decaprenylphosphoryl-beta-D-ribofuranose-2'-epimerase, thus blocking biosynthesis of arabin ...

American Association for the Advancement of Science2012

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.

Biosynthesis

NCoR Repression of LXRs Restricts Macrophage Biosynthesis of Insulin-Sensitizing Omega 3 Fatty Acids

Corrinoid auxotrophy in the obligate organohalide respiring Dehalobacter restrictus

Diversity of cobalamin riboswitches in the corrinoid-producing organohalide respirer Desulfitobacterium hafniense

Catalytic Friedel-Crafts Reaction of Aminocyclopropanes

Photodynamics of Lys+-Trp Protein Motifs: Hydrogen Bonds Ensure Photostability

On-the-Fly Kinetics of Enzymatic Racemization Using Deuterium NMR in DNA-Based Chiral Oriented Media

Nafion (R)/histidine functionalized carbon nanotube: High-performance fuel cell membranes

Genome-wide mapping of Myc binding and gene regulation in serum-stimulated fibroblasts

Kinetic modeling of the yeast sphingolipid metabolism identifies prevalent mutant strains through integration of lipidomic data profiles

Structural Basis for Benzothiazinone-Mediated Killing of Mycobacterium tuberculosis

Graph Chatbot

Chat with Graph Search

Corrinoid auxotrophy in the obligate organohalide respiring Dehalobacter restrictus

NCoR Repression of LXRs Restricts Macrophage Biosynthesis of Insulin-Sensitizing Omega 3 Fatty Acids

Diversity of cobalamin riboswitches in the corrinoid-producing organohalide respirer Desulfitobacterium hafniense

Photodynamics of Lys+-Trp Protein Motifs: Hydrogen Bonds Ensure Photostability

Nafion (R)/histidine functionalized carbon nanotube: High-performance fuel cell membranes

Kinetic modeling of the yeast sphingolipid metabolism identifies prevalent mutant strains through integration of lipidomic data profiles

On-the-Fly Kinetics of Enzymatic Racemization Using Deuterium NMR in DNA-Based Chiral Oriented Media

Genome-wide mapping of Myc binding and gene regulation in serum-stimulated fibroblasts

Structural Basis for Benzothiazinone-Mediated Killing of Mycobacterium tuberculosis

Catalytic Friedel-Crafts Reaction of Aminocyclopropanes