Publications related to Genome-wide association study

Coexistence of two distinct Sulfurospirillum populations respiring tetrachloroethene-genomic and kinetic considerations

Christof Holliger, Géraldine Florence Buttet, Alexandra Marie Murray, Mélissa Burion

Two anaerobic bacterial consortia, each harboring a distinct Sulfurospirillum population, were derived from a 10 year old consortium, SL2, previously characterized for the stepwise dechlorination of tetrachloroethene (PCE) to cis-dichloroethene (cis-DCE) v ...

2018

PWMScan: a fast tool for scanning entire genomes with a position-specific weight matrix

Giovanna Ambrosini, Philipp Bucher, Romain Fernand Pietro Groux

Transcription factors (TFs) regulate gene expression by binding to specific short DNA sequences of 5 to 20-bp to regulate the rate of transcription of genetic information from DNA to messenger RNA. We present PWMScan, a fast web-based tool to scan server-r ...

2018

Optimal Load Sharing for Serial Compressors via Modifier Adaptation

Dominique Bonvin, Timm Faulwasser, René Uwe Schneider, Predrag Milosavljevic

This paper investigates the optimal load-sharing problem of serial gas compressors in the presence of plant-model mismatch. The problem is formulated as a static real-time optimization task that is solved via modifier adaptation for interconnected systems. ...

IEEE2018

SQC: Secure Quality Control for Meta-Analysis of Genome-Wide Association Studies

Jean-Pierre Hubaux, Jacques Fellay, Zhicong Huang, Huang Lin

Motivation: Due to the limited power of small-scale genome-wide association studies (GWAS), researchers tend to collaborate and establish a larger consortium in order to perform large-scale GWAS. Genome-wide association meta-analysis (GWAMA) is a statistic ...

Oxford University Press2017

Efficient inference for genetic association studies with multiple outcomes

Anthony Christopher Davison, Jörg Hager, Hélène Ruffieux

Combined inference for heterogeneous high-dimensional data is critical in modern biology, where clinical and various kinds of molecular data may be available from a single study. Classical genetic association studies regress a single clinical outcome on ma ...

Oxford University Press2017

Bayesian association scan reveals loci associated with human lifespan and linked biomarkers

Johan Auwerx, Bart Deplancke, Murielle Bochud, Hao Li, Vincenzo Sorrentino, Maria Litovchenko, Roel Paulus Josephus Bevers, Sina Rüeger, Andrea Komljenovic

The enormous variation in human lifespan is in part due to a myriad of sequence variants, only a few of which have been revealed to date. Since many life-shortening events are related to diseases, we developed a Mendelian randomization-based method combini ...

Nature Publishing Group2017

GETPrime 2.0: gene- and transcript-specific qPCR primers for 13 species including polymorphisms

Bart Deplancke, Jacques Rougemont

GETPrime (http://bbcftools.epfl.ch/getprime) is a database with a web frontend providing geneand transcript-specific, pre-computed qPCR primer pairs. The primers have been optimized for genome-wide specificity and for allowing the selective amplification o ...

Oxford University Press2017

High performance computation of landscape genomic models including local indicators of spatial association

Stéphane Joost, Sylvie Stucki, Pierre Taberlet

With the increasing availability of both molecular and topo-climatic data, the main challenges facing landscape genomics — i.e. the combination of landscape ecology with population genomics — include processing large numbers of models and distinguishing be ...

Wiley-Blackwell2017

Genome-to-genome analysis highlights the effect of the human innate and adaptive immune systems on the hepatitis C virus

Jacques Fellay, Istvan Bartha, Nimisha Chaturvedi, David Smith

Outcomes of hepatitis C virus (HCV) infection and treatment depend on viral and host genetic factors. Here we use human genome-wide genotyping arrays and new whole-genome HCV viral sequencing technologies to perform a systematic genome-to-genome study of 5 ...

Nature Publishing Group2017

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.

Genome-wide association study

Coexistence of two distinct Sulfurospirillum populations respiring tetrachloroethene-genomic and kinetic considerations

PWMScan: a fast tool for scanning entire genomes with a position-specific weight matrix

Optimal Load Sharing for Serial Compressors via Modifier Adaptation

Evaluating the Impact of Functional Genetic Variation on HIV-1 Control

SQC: Secure Quality Control for Meta-Analysis of Genome-Wide Association Studies

Efficient inference for genetic association studies with multiple outcomes

Bayesian association scan reveals loci associated with human lifespan and linked biomarkers

GETPrime 2.0: gene- and transcript-specific qPCR primers for 13 species including polymorphisms

High performance computation of landscape genomic models including local indicators of spatial association

Genome-to-genome analysis highlights the effect of the human innate and adaptive immune systems on the hepatitis C virus

Graph Chatbot

Chat with Graph Search

Evaluating the Impact of Functional Genetic Variation on HIV-1 Control

SQC: Secure Quality Control for Meta-Analysis of Genome-Wide Association Studies

GETPrime 2.0: gene- and transcript-specific qPCR primers for 13 species including polymorphisms

PWMScan: a fast tool for scanning entire genomes with a position-specific weight matrix

Optimal Load Sharing for Serial Compressors via Modifier Adaptation

Coexistence of two distinct Sulfurospirillum populations respiring tetrachloroethene-genomic and kinetic considerations

Bayesian association scan reveals loci associated with human lifespan and linked biomarkers

Efficient inference for genetic association studies with multiple outcomes

Genome-to-genome analysis highlights the effect of the human innate and adaptive immune systems on the hepatitis C virus

High performance computation of landscape genomic models including local indicators of spatial association