The war on drugs is a global campaign, led by the United States federal government, of drug prohibition, military aid, and military intervention, with the aim of reducing the illegal drug trade in the United States. The initiative includes a set of drug policies that are intended to discourage the production, distribution, and consumption of psychoactive drugs that the participating governments and the United Nations have made illegal. The term was coined by President Richard Nixon and popularized by the media shortly after a press conference given on June 18, 1971 - the day after publication of a special message from President Nixon to the Congress on Drug Abuse Prevention and Control - during which he declared drug abuse "public enemy number one". That message to the Congress included text about devoting more federal resources to the "prevention of new addicts, and the rehabilitation of those who are addicted" but that part did not receive the same public attention as the term "war on drugs". Two years prior to this, Nixon had formally declared a "war on drugs" that would be directed toward eradication, interdiction, and incarceration. In 2015, the Drug Policy Alliance, which advocates for an end to the War on Drugs, estimated that the United States spends 51billionannuallyontheseinitiatives,andin2021,after50yearsofthedrugwar,othershaveestimatedthattheUShasspentacumulative1 trillion on it.
On May 13, 2009, Gil Kerlikowske - the Director of the Office of National Drug Control Policy (ONDCP) - signaled that the Barack Obama administration did not plan to significantly alter drug enforcement policy, but also that the administration would not use the term "War on Drugs", because Kerlikowske considers the term to be "counter-productive". ONDCP's view is that "drug addiction is a disease that can be successfully prevented and treated... making drugs more available will make it harder to keep our communities healthy and safe".
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This course introduces the student to the fudamentals of pharmacology, pharmacokinetics and drug-receptor interactions. It discusses also pharmacogenetics and chronopharmacology, to exemplify the chal
The Single Convention on Narcotic Drugs, 1961 (Single Convention, 1961 Convention, or C61) is an international treaty that controls activities (cultivation, production, supply, trade, transport) of specific narcotic drugs and lays down a system of regulations (licenses, measures for treatment, research, etc.) for their medical and scientific uses; it also establishes the International Narcotics Control Board. The Single Convention was adopted in 1961 and amended in 1972.
A psychoactive drug, psychopharmaceutical, psychoactive agent, or psychotropic drug is a chemical substance that changes the function of the nervous system and results in alterations of perception, mood, cognition, and behavior. These substances may be used medically, recreationally, for spiritual reasons (for example, by altering one's consciousness, as with entheogens for ritual, spiritual, or shamanic purposes), or for research. Some categories of psychoactive drugs may be prescribed by physicians and other healthcare practitioners because of their therapeutic value.
The Sandinista National Liberation Front (Frente Sandinista de Liberación Nacional, FSLN) is a left-wing political party in Nicaragua. Its members are called Sandinistas (sandiˈnistas) in both English and Spanish. The party is named after Augusto César Sandino, who led the Nicaraguan resistance against the United States occupation of Nicaragua in the 1930s. The FSLN overthrew Anastasio Somoza Debayle in the 1979 Nicaraguan Revolution, ending the Somoza dynasty, and established a revolutionary government in its place.
Cyclic peptides combine a number of favorable properties that make them attractive for drug development. Today, more than 40 therapeutics based on cyclic peptides are in use, and new, powerful technologies for their development suggest that this number cou ...
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Retinoblastoma is a rare childhood cancer of the eye. Of the small number of drugs are used to treat retinoblastoma, all have been repurposed from drugs developed for other conditions. In order to find drugs or drug combinations better suited to the improv ...
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Chemical space maps help visualize similarities within molecular sets. However, there are many different molecular similarity measures resulting in a confusing number of possible comparisons. To overcome this limitation, we exploit the fact that tools desi ...