Related publications (32)

Susceptibility of Enterovirus B strains to disinfectants and heat

Simon Meister

The susceptibility of waterborne viruses to different inactivating treatments is acknowledged to vary between viruses and even between closely related strains, yet the extent of this variation, or the underlying mechanisms, are not known. Here, different e ...
EPFL2019

Persistence of sewage-borne enteroviruses through chlorination treatment

Jade Brandani

Enteroviruses are a leading cause in a diversity of severe human diseases worldwide and the presence of these viruses in recreational water can present a risk for human health. Viruses' capacity to persist in the outside environment is limited but some vir ...
2019

Relationship Between Inactivation and Genome Damage of Human Enteroviruses Upon Treatment by UV254, Free Chlorine, and Ozone

Tamar Kohn, Virginie Bachmann, Suzanne Marie Young, Jason Robert Torrey

Quantitative PCR (qPCR) is a convenient tool for monitoring virus concentrations in water and wastewater treatment trains, though it only informs about virus presence, but not infectivity. This limitation can be overcome if the relationship between infecti ...
2019

Adaptation of waterborne echovirus to warm habitats enhances disinfection resistance

Tamar Kohn, Anna Carratala Ripolles, Virginie Bachmann

Because of their high mutation rate, enteric virus populations excreted from a host are not clonal, but rather consist of a mutant cloud with many different genetic variants. Among these variants, the susceptibility to environmental stressors (e.g., temper ...
2019

Inactivation of waterborne viruses by ozone: Kinetics and mechanisms

Camille Wolf

The growing world population, in conjunction with climate change, cases the global water de-mand to increase. It is, therefore, crucial to protect existing water resources from chemical pollution and contamination by pathogens. An increasingly popular stra ...
EPFL2019

Microorganisms from surface waters contribute to the inactivation of human echovirus 11: toward biocontrol of viral pathogens?

Tamar Kohn, Anna Carratala Ripolles, Margot Ninon Lauren Olive

Human viruses are widespread as contaminants in surface waters and represent a significant health risk. Viral pathogens can persist in aquatic ecosystems and cause infections via contaminated water or food. Among the different factors governing the environ ...
2019

Variability in Disinfection Resistance between Currently Circulating Enterovirus B Serotypes and Strains

Tamar Kohn, Simon Meister, Marius Klinger, Matthew Eric Verbyla

The susceptibility of waterborne viruses to disinfection is known to vary between viruses and even between closely related strains, yet the extent of this variation is not known. Here, different enteroviruses (six strains of coxsackievirus B5, two strains ...
2018

Kinetics of inactivation of waterborne enteric viruses by ozone

Urs von Gunten, Tamar Kohn, Camille Wolf

Ozone is an effective disinfectant against all types of waterborne pathogens. However, accurate and quantitative kinetic data regarding virus inactivation by ozone is scarce, due to the experimental challenges associated with the high reactivity of ozone t ...
2018

Experimental adaptation of human echovirus 11 to ultraviolet radiation leads to tolerance to disinfection and resistance to ribavirin

Tamar Kohn, Anna Carratala Ripolles, Virginie Bachmann, Jeffrey David Jensen, Qingxia Zhong, Hyunjin Shim

Ultraviolet light in the UVC range is a commonly used disinfectant to control viruses in clinical settings and water treatment. Here, we employed an experimental evolution approach to investigate the adaptation of human echovirus 11 to disinfection by UVC, ...
2017

Multi-resistance of human enterovirus to UV-C disinfection and mutagenic nucleoside analogs

Tamar Kohn, Anna Carratala Ripolles, Virginie Bachmann, Qingxia Zhong

Disinfection is an important strategy to control the environmental transmission of human viruses. Specifically, UV254 is increasingly used to disinfect from clinical items or surfaces to drinking water. RNA virus populations have high mutation rates and la ...
2016

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