Concept
Hereditary nonpolyposis colorectal cancer
Related publications (68)
Transposable elements mediate genetic effects altering the expression of nearby genes in colorectal cancer
Didier Trono, Evaristo Jose Planet Letschert, Nikolaos Lykoskoufis
Transposable elements (TEs) are prevalent repeats in the human genome, play a significant role in the regulome, and their disruption can contribute to tumorigenesis. However, TE influence on gene expression in cancer remains unclear. Here, we analyze 275 n ...
2024Mutation-Attention (MuAt): deep representation learning of somatic mutations for tumour typing and subtyping
Background: Cancer genome sequencing enables accurate classification of tumours and tumour subtypes. However, prediction performance is still limited using exome-only sequencing and for tumour types with low somatic mutation burden such as many paediatri ...
2023Gallocin A, an Atypical Two-Peptide Bacteriocin with Intramolecular Disulfide Bonds Required for Activity
Streptococcus gallolyticus subsp. gallolyticus (SGG) is an opportunistic gut pathogen associated with colorectal cancer. We previously showed that colonization of the murine colon by SGG in tumoral conditions was strongly enhanced by the production of gall ...
AMER SOC MICROBIOLOGY2023