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A divergent and regiocontrolled Pd-catalyzed domino sequence involving an intramol. N-arylation and an intermol. Heck reaction has been developed, providing rapid access to functionalized benzodiazepine-2,5-diones, e.g. I. The starting materials were synth ...
To study the physicochemical properties of the DTTA chelating moiety (H4DTTA = diethylenetriaminetetraacetic acid = N,N′-[iminobis(ethane-2,1-diyl)]bis[N-(carboxymethyl)glycine]), used in several compounds proposed as magnetic resonance imaging (MRI) contr ...
Synergic effect of iron and copper salts as catalysts for the Sonogashira–Hagihara cross-couplings of aryl iodides with terminal alkynes is demonstrated. High yields of cross- coupled products are obtained under conditions that are smoother than those usin ...
This article presents the design of the inductive links of remotely powered wireless cortical implants for minimum interference from the power link to the data link. This interference is minimized by changing the orientation of the inductors. Different ori ...
Since contrasts agents are used in magnetic resonance imaging (MRI), numerous efforts have been done to increase their relaxivity (parameter allowing to quantify contrast agent efficiency). Few years ago, the Merbach group developed the chelating agent DTT ...
The catalytic hydrocarboxylation of linear alkenes to carboxylic acids using supercritical carbon dioxide as a solvent was studied. High selectivities in acids have been obtained. The best results were achieved when adding a perfluorinated surfactant to th ...
This feature article provides a compilation of tools available for preparing well-defined peptide/protein–polymer conjugates, which are defined as hybrid constructs combining (i) a defined number of peptide/protein segments with uniform chain lengths and d ...
This work describes the synthesis and characterization of boronic acid-based supramolecular structures. Macrocycles, dendritic structures, polymers, rotaxanes, and cages were assembled using four types of reversible reactions. The key point of the strategy ...
We perform in this paper a kinetic study of the photoelectrochemical responses of nanoporous thin photoactive films. The films were fabricated by by a layer-by-layer assembly of positively charged polyelectrolytes (poly-L- Lysine, pLys) and negatively char ...
Palladium-catalyzed intramol. Suzuki-Miyaura reaction of linear tripeptide afforded the 16-membered DEFG ring of complestatin I in good yield with an excellent atropdiastereoselectivity. Acidic treatment of I triggers a stereospecific rearrangement leading ...