Concept
Hyperandrogenism
Related publications (10)
Microbes support enhanced nitrogen requirements of coral holobionts in a high CO 2 environment
Nils Rädecker, Gabriela Hannah Holligan Perna
Ocean acidification is posing a threat to calcifying organisms due to the increased energy requirements of calcification under high CO2 conditions. The ability of scleractinian corals to cope with future ocean conditions will thus depend on their ability t ...
2021A high resolution LC-MS targeted method for the concomitant analysis of 11 contraceptive progestins and 4 steroids
Cathrin Brisken, Jonathan Paz Montoya, Marc Moniatte, Fabio De Martino, Marie Shamseddin, Csaba Ferenc László, Alexandre Béguin
In the context of hormonal contraception and hormone replacement therapy (HRT), many women are exposed to exogenous hormones. Current use of hormonal contraception with combined ethinyl estradiol and different progestins bestows a breast cancer relative ri ...
2019Characterization of cancer stem cell subpopulations from patient-derived xenografts of advanced prostate cancer
Marina Bice Manuela Menna, Markus Germann
Androgen-deprivation therapy is the standard treatment for prostate cancer. Despite the initial response, a fraction of cases manifest progression to castration-resistant prostate cancer. PCa recurrence is possibly due to androgen-independent cancer stem c ...
AMER ASSOC CANCER RESEARCH2018Bile acid-FXR alpha pathways regulate male sexual maturation in mice
The bile acid receptor Farnesol-X-Receptor alpha (FRX alpha) is a member of the nuclear receptor superfamily. FRX alpha is expressed in the interstitial compartment of the adult testes, which contain the Leydig cells. In adult, short term treatment (12 hou ...
Impact Journals Llc2016No Scope for Social Modulation of Steroid Levels in a Year-Round Territorial Damselfish
Both latitude and mating system have been proposed to shape relationships between steroid hormone levels and social behavior. Recently it has been postulated that species with long lasting non-seasonal territorial behavior have low androgen responsiveness. ...
Wiley-Blackwell2015VEGFR-3 Neutralization Inhibits Ovarian Lymphangiogenesis, Follicle Maturation, and Murine Pregnancy
Didier Trono, Jeffrey Alan Hubbell, Melody Swartz, Witold Waldemar Kilarski, Joseph Rutkowski, Seung Tae Lee, Miriella Carmela Pasquier, Jong Eun Ihm, Vivianne Greenwood
Lymphatic vessels surround follicles within the ovary, but their roles in folliculogenesis and pregnancy, as well as the necessity of Lymphangiogenesis in follicle maturation and health, are undefined. We used systemic delivery of mF4-31C1, a specific anta ...
Elsevier Science Inc2013How elevated pCO2 modifies total and metabolically active bacterial communities in the rhizosphere of two perennial grasses grown under field conditions
The response of total (DNA-based analysis) and active (RNA-based analysis) bacterial communities to a pCO2 increase under field conditions was assessed using two perennial grasses: the nitrophilic Lolium perenne and the oligonitrophilic Molinia coerulea. P ...
2006Identification of molecular apocrine breast tumours by microarray analysis
Cathrin Brisken, Darlene Goldstein, Maryse Fiche
Previous microarray studies on breast cancer identified multiple tumour classes, of which the most prominent, named luminal and basal, differ in expression of the oestrogen receptor alpha gene (ER). We report here the identification of a group of breast tu ...
2005Sterols and gene expression: control of affluence
Johan Auwerx, Kristina Schoonjans
Intracellular and extracellular cholesterol levels are tightly maintained within a narrow concentration range by an intricate transcriptional control mechanism. Excess cholesterol can be converted into oxysterols, signaling molecules, which modulate the ac ...
2000Transcriptional regulation of cholesterol metabolism [Regulation transcriptionnelle du metabolisme du cholesterol]
Johan Auwerx, Kristina Schoonjans
Sterols and cholesterol in particular are lipids that have been studied exhaustively in view of their vital role in diverse cellular functions. Recently, it has been recognized that cholesterol is not only an essential component for the formation of membra ...
1999