ScopolamineScopolamine, also known as hyoscine, or Devil's Breath, is a natural or synthetically produced tropane alkaloid and anticholinergic drug that is used as a medication to treat motion sickness and postoperative nausea and vomiting. It is also sometimes used before surgery to decrease saliva. When used by injection, effects begin after about 20 minutes and last for up to 8 hours. It may also be used orally and as a transdermal patch since it has been long known to have transdermal bioavailability.
Witches' SabbathA Witches' Sabbath is a purported gathering of those believed to practice witchcraft and other rituals. The phrase became popular in the 20th century. Prior to the late 19th century, it is difficult to locate any English use of the term sabbath to denote a supposed gathering of witches. The phrase is used by Henry Charles Lea in his History of the Inquisition of the Middle Ages (1888).
European witchcraftEuropean witchcraft is a multifaceted historical and cultural phenomenon that unfolded over centuries, leaving a mark on the continent's social, religious, and legal landscapes. The roots of European witchcraft trace back to classical antiquity when concepts of magic and the supernatural were interwoven into societal beliefs. Ancient Rome, then a pagan society, had laws against harmful magic. During the Middle Ages, misogynist views of women led to the association of women and malevolent witchcraft, as accusations of heresy and devil worship grew more prevalent.
Amanita muscariaAmanita muscaria, commonly known as the fly agaric or fly amanita, is a basidiomycete of the genus Amanita. Native throughout the temperate and boreal regions of the Northern Hemisphere, Amanita muscaria has been unintentionally introduced to many countries in the Southern Hemisphere, generally as a symbiont with pine and birch plantations, and is now a true cosmopolitan species. It associates with various deciduous and coniferous trees.
Muscarinic acetylcholine receptorMuscarinic acetylcholine receptors, or mAChRs, are acetylcholine receptors that form G protein-coupled receptor complexes in the cell membranes of certain neurons and other cells. They play several roles, including acting as the main end-receptor stimulated by acetylcholine released from postganglionic fibers in the parasympathetic nervous system. Muscarinic receptors are so named because they are more sensitive to muscarine than to nicotine.
AtropineAtropine is a tropane alkaloid and anticholinergic medication used to treat certain types of nerve agent and pesticide poisonings as well as some types of slow heart rate, and to decrease saliva production during surgery. It is typically given intravenously or by injection into a muscle. Eye drops are also available which are used to treat uveitis and early amblyopia. The intravenous solution usually begins working within a minute and lasts half an hour to an hour. Large doses may be required to treat some poisonings.
