Concept
Gram-negative bacteria
Related publications (167)
Capsular Polysaccharide Restrains Type VI Secretion in Acinetobacter baumannii
Melanie Blokesch, Loriane Bader, Mary-Claude Croisier-Coeytaux, Nicolas Olmo Flaugnatti
The type VI secretion system (T6SS) is a sophisticated, contact-dependent nanomachine involved in interbacterial competition. To function effectively, the T6SS must penetrate the membranes of both attacker and target bacteria. Structures associated with th ...
2024Bactericidal effect of tetracycline in E. coli strain ED1a may be associated with ribosome dysfunction
Camille Véronique Bernadette Goemans, Christian Eugen Zimmerli, Martin Beck
Ribosomes translate the genetic code into proteins. Recent technical advances have facilitated in situ structural analyses of ribosome functional states inside eukaryotic cells and the minimal bacterium Mycoplasma. However, such analyses of Gram-negative b ...
2024Simple optical nanomotion method for single-bacterium viability and antibiotic response testing
Sandor Kasas, María Inés Villalba, Allan Bonvallat, Eugenia Rossetti
Antibiotic resistance is nowadays a major public health issue. Rapid antimicrobial susceptibility tests (AST) are one of the options to fight this deadly threat. Performing AST with single-cell sensitivity that is rapid, cheap, and widely accessible, is ch ...
NATL ACAD SCIENCES2023Sulfurospirillum diekertiae sp. nov., a tetrachloroethene-respiring bacterium isolated from contaminated soil
Christof Holliger, Julien Maillard, Junxiong Wang
Two anaerobic, tetrachloroethene- (PCE-) respiring bacterial isolates, designated strain ACSDCE T and strain ACSTCE, were characterized using a polyphasic approach. Cells were Gram-stain-negative, motile, non-spore-forming and shared a vibrioid- to spirill ...
2023Functional characterization of Drosophila melanogaster immune effectors
Drosophila melanogaster, commonly known as the "fruit fly", is a genetically tractable model organism widely used to study biological processes, notably the innate immune system. The advent of novel genome editing technologies, such as the CRISPR-Cas9 syst ...
EPFL2023Biofilm morphogenesis on soft hydrogels
Bacteria often colonize their environment in the form of surface attached multicellular communities called biofilms. Biofilms grow from surface-attached cells that undergo division while self-embedding in a viscoelastic matrix. Biofilms grow at the surface ...
EPFL2023Antimicrobial susceptibility testing with integrated photonic crystal optical tweezers
The abusive use of antimicrobial drugs during the last eighty years has favoured the natural selection of resistant pathogens able to neutralise drugs efficiently. Nowadays, antimicrobial resistance contributes to millions of deaths yearly, threatens the e ...
EPFL2023The Effects of Spatial Organization and Fluid Flow on the Social Interactions in Microbial Communities
Bacteria often engage in social interactions with neighbouring bacteria. Ecosystems which are subjected to social interactions have been widely studied in well mixed settings such as test tubes, allowing us to identify the cellular components contributingt ...
EPFL2023A Rapidly Responsive Sensor for Wireless Detection of Early and Mature Microbial Biofilms
Hubert Girault, Wanderson Oliveira Da Silva, Andreas Stephan Lesch, Bhawna Nagar
Biofilm-associated infections, which are able to resist antibiotics, pose a significant challenge in clinical treatments. Such infections have been linked to various medical conditions, including chronic wounds and implant-associated infections, making the ...
WILEY-V C H VERLAG GMBH2023In vitro synergistic action of TAT-RasGAP 317-326 peptide with antibiotics against Gram-negative pathogens
Objectives: Multidrug-resistant (MDR) bacteria are a continuously increasing threat for medicine, caus-ing infections recalcitrant to antibiotics. Antimicrobial peptides (AMPs) were identified as alternatives to antibiotics, being naturally occurring short ...
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