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Grazia Vizzarro
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Vibrio cholerae pathogenicity island 2 encodes two distinct types of restriction systems
Melanie Blokesch, David William Adams, Alexandre Lemopoulos, Grazia Vizzarro
In response to predation by bacteriophages and invasion by other mobile genetic elements such as plasmids, bacteria have evolved specialised defence systems that are often clustered together on genomic islands. The O1 El Tor strains of Vibrio cholerae resp ...
2024Recent advances in therapeutic targets identification and development of treatment strategies towards Pseudomonas aeruginosa infections
The opportunistic human pathogen Pseudomonas aeruginosa is the causal agent of a wide variety of infections. This non-fermentative Gram-negative bacillus can colonize zones where the skin barrier is weakened, such as wounds or burns. It also causes infecti ...
BMC2023In vitro synergistic action of TAT-RasGAP 317-326 peptide with antibiotics against Gram-negative pathogens
Objectives: Multidrug-resistant (MDR) bacteria are a continuously increasing threat for medicine, caus-ing infections recalcitrant to antibiotics. Antimicrobial peptides (AMPs) were identified as alternatives to antibiotics, being naturally occurring short ...
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