Concept

Cyclic nucleotide–gated ion channel

Related publications (67)

Optimal feedback schemes over unknown channels

Communication over unknown discrete memoryless channels with instantaneous and perfect feedback is considered. For a given set of channels we define a notion of optimal coding schemes in terms of achievable rate and error exponent, and prove the existence ...

2004

Highly electrically insulating tethered lipid bilayers for probing the function of Ion channel proteins

Horst Vogel, Samuel Terrettaz, Michael Mayer

A method is presented to form gold-electrode-tethered lipid bilayers with exceptionally high elec. resistances. Elec. impedance spectroscopy is used to monitor the bilayer incorporation of a ligand-gated ion channel protein and the modulation of its channe ...

2003

Characterization of the Ligand-binding Site of the Serotonin 5-HT3 Receptor: The Role of Glutamate Residues 97, 224,and 235

Horst Vogel, Rudolf Hovius, Horst Pick, Christoph Schreiter, Matteo Costioli

Ligand-gated ion channels of the Cys loop family are receptors for small amine-contg. neurotransmitters. Charged amino acids are strongly conserved in the ligand-binding domain of these receptor proteins. To investigate the role of particular residues in l ...

2003

Bioanalytical reagent, method for production thereof, sensor platforms and detection methods based on use of said bioanalytical reagent

Horst Vogel, Horst Pick

The invention relates to various embodiments of a bioanal. reagent with at least one vesicle, generated from a living cell, and at least one receptor for study of signal transduction. The invention further relates to methods for prodn. of said bioanal. rea ...

(Ecole Polytechnique Federale de Lausanne, Switz.; Zeptosens A.-G.).2002

Characterization of a transmembrane receptor protein by fluorescence correlation spectroscopy

Horst Vogel, Rudolf Hovius, Horst Pick

Fluorescence Correlation Spectroscopy (FCS) is a suitable technique to investigate biomol. interactions. The advantage of FCS lies in its wide dynamic range in the time and concn. domain, its sensitivity, and thus in the small amt. of material needed. The ...

2001

Evidence for a small anion-selective channel in the cell wall of Mycobacterium bovis BCG besides a wide cation-selective pore

Stewart Cole

Two channels were observed in extracts of whole Mycobacterium bovis BCG cells using organic solvents and detergents. The channels derived from organic solvent treatment had a single-channel conductance of about 4.0 nS in 1 M KCl in lipid bilayer membranes ...

1999

The lectin-like domain of tumor necrosis factor-alpha increases membrane conductance in microvascular endothelial cells and peritoneal macrophages

Françoise Gisou van der Goot Grunberg

Herein, we show that TNF exerts a pH-dependent increase in membrane conductance in primary lung microvascular endothelial cells and peritoneal macrophages. This effect was TNF receptor-independent, since it also occurred in cells isolated from mice deficie ...

1999

Expression of ligand-gated ion channels with the Semliki Forest virus expression system

Horst Vogel, Rudolf Hovius

Two types of ligand-gated ion channels were expressed with the Semliki Forest virus (SFV) expression system. The cDNAs for mouse serotonin 5-HT3 receptor and rat and human purinoreceptor P2x subtypes were introduced into the pSFV1 vector. In vitro transcri ...

1997

The Semliki Forest virus system: receptor expression and scale-up

Horst Vogel, Rudolf Hovius, Alain Bernard

The highly efficient Semliki Forest virus (SFV) system has been applied to express several recombinant 7TM receptors and ligand-gated ion channels. High affinity binding and functional coupling to G proteins were obtained for the receptors. The ligand-gate ...

1997

Novel benzo-15-crown-5 functionalized α-olefin/CO terpolymers for membrane applications

Harm-Anton Klok

The synthesis of a benzo-15-crown-5 functionalized α-olefin (4′-(undec-10-enylcarboxylate)benzo-15-crown-5, 5) and its terpolymerization with carbon monoxide and various α-olefins are described. A decline of the glass transition temperatures (Tg) of the co ...

1997

Graph Chatbot

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.