Publications related to Recombinant DNA

Vibrio cholerae pathogenicity island 2 encodes two distinct types of restriction systems

Melanie Blokesch, David William Adams, Alexandre Lemopoulos, Grazia Vizzarro

In response to predation by bacteriophages and invasion by other mobile genetic elements such as plasmids, bacteria have evolved specialised defence systems that are often clustered together on genomic islands. The O1 El Tor strains of Vibrio cholerae resp ...

2024

Living Photovoltaics based on Recombinant Expression of MtrA Decaheme in Photosynthetic Bacteria

Ardemis Anoush Boghossian, Melania Reggente, Mohammed Mouhib, Alessandra Antonucci, Nils Schürgers, Sara Politi

At the center of microbial bioelectricity applications lies the critical need to express foreign heme proteins that are capable of redirecting the electron flux of the cell’s metabolism. This study presents bioengineered Synechocystis sp. PCC 6803 cells ca ...

2023

C2CAplus: A One-Pot Isothermal Circle-to-Circle DNA Amplification System

Sebastian Maerkl, Laura Sophie Grasemann

Rolling circle amplification (RCA) is a widely used DNA amplification method that uses circular template DNA as input and produces multimeric, linear single- or double-stranded DNA. Circle-to-circle amplification (C2CA) has further expanded this method by ...

Washington2023

Tailoring the Hybridization Density of DNA Biosensors through Tunable Surface Functionalization

Sandrine Gerber, Mounir Driss Mensi, Perrine Agnes Edith Robin, Pauline Skigin, Lucas Mayoraz

DNA biosensors are promising candidates for the development of point-of-care diagnosis methods. They can be inserted in microfluidic platforms, are often non-expensive, and can be produced for a variety of targeted analytes. However, their development face ...

2023

A field-capable rapid plant DNA extraction protocol using microneedle patches for botanical surveying and monitoring

Sebastian Maerkl, Nicolas Rémi Adam, Jonathan Selz

PremiseA novel protocol for rapid plant DNA extraction using microneedles is proposed, which supports botanic surveys, taxonomy, and systematics. This protocol can be conducted in the field with limited laboratory skills and equipment. The protocol is vali ...

WILEY2023

Two defence systems eliminate plasmids from seventh pandemic Vibrio cholerae

Melanie Blokesch, David William Adams, Milena Jadwiga Jaskolska

Horizontal gene transfer can trigger rapid shifts in bacterial evolution. Driven by a variety of mobile genetic elements—in particular bacteriophages and plasmids—the ability to share genes within and across species underpins the exceptional adaptability o ...

2022

The enhancement of DNA fragmentation in a bench top ultrasonic water bath with needle-induced air bubbles: Simulation and experimental investigation

Martinus Gijs, Thomas Lehnert, Yang Liu, Lin Sun

Shearing DNA to a certain size is the first step in many medical and biological applications, especially in next-generation gene sequencing technology. In this article, we introduced a highly efficient ultrasonic DNA fragmentation method enhanced by needle ...

AIP Publishing2022

Novel irreversible covalent BTK inhibitors discovered using DNA-encoded chemistry

Sevan Mleh Habeshian, Ying Zhang

Libraries of DNA-Encoded small molecules created using combinatorial chemistry and synthetic oligonucleotides are being applied to drug discovery projects across the pharmaceutical industry. The majority of reported projects describe the discovery of rever ...

PERGAMON-ELSEVIER SCIENCE LTD2021

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Recombinant DNA

Vibrio cholerae pathogenicity island 2 encodes two distinct types of restriction systems

Il-10 expressing cells for enhanced cancer immunotherapies

Living Photovoltaics based on Recombinant Expression of MtrA Decaheme in Photosynthetic Bacteria

C2CAplus: A One-Pot Isothermal Circle-to-Circle DNA Amplification System

Tailoring the Hybridization Density of DNA Biosensors through Tunable Surface Functionalization

A field-capable rapid plant DNA extraction protocol using microneedle patches for botanical surveying and monitoring

Solving the mystery of the missing plasmids in seventh pandemic Vibrio cholerae strains

Two defence systems eliminate plasmids from seventh pandemic Vibrio cholerae

The enhancement of DNA fragmentation in a bench top ultrasonic water bath with needle-induced air bubbles: Simulation and experimental investigation

Novel irreversible covalent BTK inhibitors discovered using DNA-encoded chemistry

Graph Chatbot

Chat with Graph Search

Tailoring the Hybridization Density of DNA Biosensors through Tunable Surface Functionalization

The enhancement of DNA fragmentation in a bench top ultrasonic water bath with needle-induced air bubbles: Simulation and experimental investigation

Novel irreversible covalent BTK inhibitors discovered using DNA-encoded chemistry

Vibrio cholerae pathogenicity island 2 encodes two distinct types of restriction systems

Il-10 expressing cells for enhanced cancer immunotherapies

Living Photovoltaics based on Recombinant Expression of MtrA Decaheme in Photosynthetic Bacteria

C2CAplus: A One-Pot Isothermal Circle-to-Circle DNA Amplification System

Solving the mystery of the missing plasmids in seventh pandemic Vibrio cholerae strains

Two defence systems eliminate plasmids from seventh pandemic Vibrio cholerae

A field-capable rapid plant DNA extraction protocol using microneedle patches for botanical surveying and monitoring