Concept

Modelling biological systems

Related publications (59)

Superparamagnetic Nanoparticles as a Powerful Systems Biology. Characterization Tool in the Physiological Context

Heinrich Hofmann, Jatuporn Salaklang, Jeffrey Alan Hubbell, Alke Fink, Marc Moniatte, Benedikt Steitz, Conlin O'Neil, Andrija Finka

Recently, functionalized superparamagnetic iron oxide nanoparticles (SPIONs) have been utilized for protein separation and therapeutic delivery of DNA and drugs. The development of new methods and tools for the targeting and identification of specific biom ...

Wiley-Blackwell2008

Computational Probability for Systems Biology

Stochastic models of biological networks properly take the randomness of molecular dynamics in living cells into account. Numerical solution approaches inspired by computational methods from applied probability can efficiently yield accurate results and ha ...

Springer2008

A Systems Approach to Measuring the Binding Energy Landscapes of Transcription Factors

Sebastian Maerkl

A major goal of systems biology is to predict the function of biological networks. Although network topologies have been successfully determined in many cases, the quantitative parameters governing these networks generally have not. Measuring affinities of ...

2007

Hybrid identification methods for the reconstruction of genetic regulatory networks

Giancarlo Ferrari Trecate

This tutorial paper considers the problem of reconstructing Genetic Regulatory Networks (GRNs) from gene expression measurements. Among various modeling frameworks that have been proposed for these biological systems, we focus on PieceWise Affine (PWA) mod ...

2007

Microfluidic Applications in Biology From Technologies to Systems Biology

Niels Erik Lion, Joël Stéphane Rossier

High-impact research articles on microfluidics and its application in biology and biotechnology. The articles have been selected from our popular Electrophoresis journal special issue. ...

Wiley-VCH2006

EPD in its twentieth year: towards complete promoter coverage of selected model organisms

Philipp Bucher, Rouayda Cavin Perier

The Eukaryotic Promoter Database (EPD) is an annotated non-redundant collection of eukaryotic POL II promoters, experimentally defined by a transcription start site (TSS). Access to promoter sequences is provided by pointers to positions in the correspondi ...

2006

Frontiers of Optical Spectroscopy: Investigating Extreme Physical Conditions with Advanced Optical Techniques

We present a review of wave packet dynamics in different systems and stress their relation to information on the ultrafast structural changes. We show how dynamical information is obtained from ultrafast optical pump-probe studies on structural changes in ...

SPRINGER2005

Precise Graphical Representation of Roles in Requirements Engineering

Alain Wegmann, Pavel Balabko

Modeling complex systems can not be done without considering a system from multiple views. Using multiple views improves model understandability. However the analysis of models that integrate multiple views is difficult. In many cases a model can be evalua ...

2003

Modelling molecular mechanisms within their cellular environment

Vassily Hatzimanikatis

Cells are too complex to model completely. This necessitates partitioning between a subsystem comprising cellular components and processes which are considered in more detail, and the balance of components and metab. of the cell. Here, this aspect of the m ...

1999

Graph Chatbot

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.