Concept

Immunoassay

Related publications (33)

Fabrication of a high aspect ratio (HAR) micropillar filter for a magnetic bead-based immunoassay

A microfluidic chip has been realized for investigating immune cell (U937) activation with lipopolysaccharide (LPS) and subsequent pro-inflammatory cytokine (Interleukin-6, IL-6) detection (Ruffert et al. Proc. EMBL Conference Microfluidics 2012a, p 184; P ...

Springer2014

Programming and use of Parylene C fluorescence as a quantitative on-chip reference

Martinus Gijs, Diego Gabriel Dupouy, Ata Tuna Ciftlik, Joan Teixidor

A large number of lab-on-a-chip applications use fluorescence for quantifying biological entities. In such applications, incorporation of a stable on-chip fluorescent reference source would be highly desirable in order to compensate for instrumental parame ...

Royal Soc Chemistry2014

Total serum IgE quantification by microfluidic ELISA using magnetic beads

Hubert Girault, Anne-Laure Gassner

The present work reports on the quantification of total IgE in human serum using a microanalytical device whose fluidics is driven by gravity and capillary forces only. Thanks to the eight parallel microchannels in each microchip, calibration and sample an ...

Springer Verlag2012

Capillary Microfluidic Chips for Point-of-Care Testing

Luc Gervais

Research on microfluidic devices for biological analysis has progressed sufficiently to be developed into point-of-care diagnostics products. The goal of this thesis is to improve multiple aspects of capillary-driven microfluidic devices. In particular, th ...

EPFL2011

MULTI-ANALYTE DETECTION FOR BIOLOGICAL FLUIDS Towards Continous Monitoring of Glucose, Ionized Calcium and pH using a Viscometric Affinity Biosensor

Peter Ryser, Eric Meurville, Christophe Boss, Frédéric Schmitt, Pablo Dosil Rosende

We present a viscometric affinity biosensor that can potentially allow continuous multi-analyte monitoring in biological fluids like blood or plasma. The sensing principle is based on the detection of viscosity changes of a polymeric solution which has a s ...

SciTePress2011

Microfluidic Chips for Point-of-Care Immunodiagnostics

Nico de Rooij, Luc Gervais, Emmanuel Delamarche

We might be at the turning point where research in microfluidics undertaken in academia and industrial research laboratories, and substantially sponsored by public grants, may provide a range of portable and networked diagnostic devices. In this Progress R ...

Wiley-Blackwell2011

Self-Assembled Liquid-Gated Zinc Oxide Nanowire Transistors

Vivek Pachauri

This thesis aims at the site-specific realization of self-assembled field-effect transistors (FETs) based on semiconducting Zinc oxide NWs and their application towards chemical and bio-sensing in liquid medium. At first, a solution based growth method for ...

EPFL2011

Optical Trapping in Microfluidic Channels for Functional and Chemical Analysis of Single Cells

Michael Werner

The physiological properties of cells are typically investigated in ensembles yielding averaged data that mask heterogeneities present in any cell population. Single-cell analysis techniques based on microfluidic "lab on a chip" (LOC) devices have recently ...

EPFL2011

Comparative genomics of Esx genes from clinical isolates of Mycobacterium tuberculosis provides evidence for gene conversion and epitope variation

Stewart Cole, Jacques Rougemont, Swapna Uplekar

The 23-membered Esx protein family is involved in the host-pathogen interactions of Mycobacterium tuberculosis. These secreted proteins are among the most immunodominant antigens recognized by the human immune system and have thus been used to develop vacc ...

2011

Comparison of Three Methods of Biocompatible Multi-Walled Carbon Nanotubes Confinement for the Development of Implantable Amperometric Adenosine-5′-Triphosphate Biosensors

Giovanni De Micheli, Sandro Carrara, Andrea Cavallini

An amperometric biosensor for adenosine 5 -triphosphate (ATP) was developed applying a competitive assay of two glucose converting enzymes: glucose oxidase (GOD) and hexokinase (HEX). Competition between GOD and HEX for glucose in presence of ATP, lead to ...

American Scientific Publishers2011

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