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Young children and adults process spatial information differently: the former use their bodies as primary reference, while adults seem capable of using abstract frames. The transition is estimated to occur between the 6th and the 12th year of age. The mech ...
NATURE PORTFOLIO2023
Grid cells are place-modulated neurons that encode the location of an agent in space, relying on the integration of various sensorimotor signals from the body. Of note, the integration of those signals is also fundamental for the agent's conscious experien ...
EPFL2021
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Topographical disorientation refers to the selective inability to orient oneself in familiar surroundings. However, to date its neural correlates remain poorly understood. Here we use quantitative lesion analysis and a lesion network mapping approach in or ...
Hoboken2024
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Objective: Structure-function coupling remains largely unknown in brain disorders. We studied this coupling during interictal epileptic discharges (IEDs), using graph signal processing in temporal lobe epilepsy (TLE). Methods: We decomposed IEDs of 17 pati ...
ELSEVIER IRELAND LTD2023
Ethics in engineering has long been an important element in engineering programmes, however these subjects are often taught at a basic learning level with little attempt to connect to demonstrative learning outcomes. In recent years there has been a step c ...
University Politècnica de Catalunya - BarcelonaTech (UPC)2022
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The researchers used a machine-learning classification approach to better understand neurological features associated with periods of wayfinding uncertainty. The participants (n = 30) were asked to complete wayfinding tasks of varying difficulty in a virtu ...
ELSEVIER SCI LTD2022
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In this paper, we will argue that the structure of the spatio-temporal pedagogical set-up and the elaboration of an evolutionary support for operations of cognition and imagination are powerful in transforming learning cultures. We develop this argument in ...
Neural computational power is determined by neuroenergetics, but how and which energy substrates are allocated to various forms of memory engram is unclear. To solve this question, we asked whether neuronal fueling by glucose or lactate scales differently ...
The immobilization of molecular catalysts imposes spatial constraints on their active site. We reveal that in bifunctional catalysis such constraints can also be utilized as an appealing handle to boost intrinsic activity through judicious control of the a ...
Multiple studies have found that increasing histone acetylation by means of histone deacetylase inhibitor (HDACi) treatment can ameliorate memory and rescue cognitive impairments, but their mode of action is not fully understood. In particular, it is uncle ...
