Concept
Retinal dehydrogenase
Related publications (4)
A reduced form of nicotinamide riboside defines a new path for NAD(+) biosynthesis and acts as an orally bioavailable NAD(+) precursor
Carlos Canto Alvarez, Richardus Houtkooper, Sofia Moco
Objective: A decay in intracellular NAD(+) levels is one of the hallmarks of physiological decline in normal tissue functions. Accordingly, dietary supplementation with NAD(+) precursors can prevent, alleviate, or even reverse multiple metabolic complicati ...
ELSEVIER2019In vivo electrical stimulation of the optic nerve and hybrid computational model for neuroprosthetic applications
Silvestro Micera, Diego Ghezzi, Samuel Charles Antoine Gilliéron, Fiorenzo Artoni, Paola Vagni, Vivien Gaillet
Blindness affects millions of people worldwide, dramatically decreasing their quality of life. Retinal dystrophies, such as age related macular degeneration and Retinitis Pigmentosa, which are leading causes of blindness in industrialized countries, curren ...
2018Mutations in ALDH1A3 Represent a Frequent Cause of Microphthalmia/Anophthalmia in Consanguineous Families
Anophthalmia or microphthalmia (A/M), characterized by absent or small eye, can be unilateral or bilateral and represent developmental anomalies due to the mutations in several genes. Recently, mutations in aldehyde dehydrogenase family 1, member A3 (ALDH1 ...
Wiley-Blackwell2014Early Steps of the Intramolecular Signal Transduction in Rhodopsin Explored by Molecular Dynamics Simulations
Ursula Röthlisberger, Leonardo Guidoni
We present mol. dynamics simulations of bovine rhodopsin in a membrane mimetic environment based on the recently refined x-ray structure of the pigment. The interactions between the protonated Schiff base and the protein moiety are explored both with the c ...
2002