Publications related to Viral shedding

Viral RNA Degradation and Diffusion Act as a Bottleneck for the Influenza A Virus Infection Efficiency

After endocytic uptake, influenza viruses transit early endosomal compartments and eventually reach late endosomes. There, the viral glycoprotein hemagglutinin (HA) triggers fusion between endosomal and viral membrane, a critical step that leads to release ...

Public Library Science2016

Multi-resistance of human enterovirus to UV-C disinfection and mutagenic nucleoside analogs

Tamar Kohn, Anna Carratala Ripolles, Virginie Bachmann, Qingxia Zhong

Disinfection is an important strategy to control the environmental transmission of human viruses. Specifically, UV254 is increasingly used to disinfect from clinical items or surfaces to drinking water. RNA virus populations have high mutation rates and la ...

2016

Inside Job: Viruses Transfer cGAMP between Cells

Andrea Ablasser, Muhammet Fatih Gülen

The DNA sensor, cyclic GMP-AMP synthase (cGAS), is essential for the detection of viral infection. In a recent issue of Science, two studies, Bridgeman et al. (2015) and Gentili et al. (2015), report a novel mechanism for propagating an antiviral signal be ...

Cell Press2015

Human genetic variation in HIV disease: beyond genome-wide association studies

Jacques Fellay

PURPOSE OF REVIEW: Rapid expansion of genomic technologies has resulted in an unprecedented ability to interrogate the impact of human genetic variation on disease. HIV-1 infection is a unique model for studying this impact because host genetic variation i ...

Lippincott Williams & Wilkins2015

Dynamics of HIV Latency and Reactivation in a Primary CD4+T Cell Model

Jacques Fellay, Christian Axel Wandall Thorball, Amalio Telenti, Istvan Bartha, Julia di Iulio

HIV latency is a major obstacle to curing infection. Current strategies to eradicate HIV aim at increasing transcription of the latent provirus. In the present study we observed that latently infected CD4+ T cells from HIV-infected individuals failed to pr ...

Public Library Science2014

GuavaH: a compendium of host genomic data in HIV biology and disease

Jacques Fellay, Amalio Telenti, Istvan Bartha

Background: There is an ever-increasing volume of data on host genes that are modulated during HIV infection, influence disease susceptibility or carry genetic variants that impact HIV infection. We created GuavaH (Genomic Utility for Association and Viral ...

BioMed Central2014

UVC inactivation of dsDNA and ssRNA viruses in water: UV fluences and a qPCR-based approach to evaluate decay on viral infectivity

Tamar Kohn, Anna Carratala Ripolles

Disinfection by low-pressure monochromatic ultraviolet (UVC) radiation (253.7 nm) became an important technique to sanitize drinking water and also wastewater in tertiary treatments. In order to prevent the transmission of waterborne viral diseases, the an ...

Springer2014

Periodic versus Intermittent Adaptive Cycles in Quasispecies Coevolution

Alexander Kevin Seeholzer

We study an abstract model for the coevolution between mutating viruses and the adaptive immune system. In sequence space, these two populations are localized around transiently dominant strains. Delocalization or error thresholds exhibit a novel interdepe ...

American Physical Society2014

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Viral shedding

Inhibition of influenza virus activity by the bovine seminal plasma protein PDC-109

Broad-spectrum Antiviral Nanoparticles

Viral RNA Degradation and Diffusion Act as a Bottleneck for the Influenza A Virus Infection Efficiency

Multi-resistance of human enterovirus to UV-C disinfection and mutagenic nucleoside analogs

Inside Job: Viruses Transfer cGAMP between Cells

Human genetic variation in HIV disease: beyond genome-wide association studies

Dynamics of HIV Latency and Reactivation in a Primary CD4+T Cell Model

GuavaH: a compendium of host genomic data in HIV biology and disease

UVC inactivation of dsDNA and ssRNA viruses in water: UV fluences and a qPCR-based approach to evaluate decay on viral infectivity

Periodic versus Intermittent Adaptive Cycles in Quasispecies Coevolution

Graph Chatbot

Chat with Graph Search

Broad-spectrum Antiviral Nanoparticles

Viral RNA Degradation and Diffusion Act as a Bottleneck for the Influenza A Virus Infection Efficiency

Inhibition of influenza virus activity by the bovine seminal plasma protein PDC-109

Multi-resistance of human enterovirus to UV-C disinfection and mutagenic nucleoside analogs

Human genetic variation in HIV disease: beyond genome-wide association studies

UVC inactivation of dsDNA and ssRNA viruses in water: UV fluences and a qPCR-based approach to evaluate decay on viral infectivity

Inside Job: Viruses Transfer cGAMP between Cells

GuavaH: a compendium of host genomic data in HIV biology and disease

Periodic versus Intermittent Adaptive Cycles in Quasispecies Coevolution

Dynamics of HIV Latency and Reactivation in a Primary CD4+T Cell Model