Concept

Andrew Huxley

Summary
Sir Andrew Fielding Huxley (22 November 1917 30 May 2012) was an English physiologist and biophysicist. He was born into the prominent Huxley family. After leaving Westminster School in central London, he went to Trinity College, Cambridge on a scholarship, after which he joined Alan Lloyd Hodgkin to study nerve impulses. Their eventual discovery of the basis for propagation of nerve impulses (called an action potential) earned them the Nobel Prize in Physiology or Medicine in 1963. They made their discovery from the giant axon of the Atlantic squid. Soon after the outbreak of the Second World War, Huxley was recruited by the British Anti-Aircraft Command and later transferred to the Admiralty. After the war he resumed research at the University of Cambridge, where he developed interference microscopy that would be suitable for studying muscle fibres. In 1952, he was joined by a German physiologist Rolf Niedergerke. Together they discovered in 1954 the mechanism of muscle contraction, popularly called the "sliding filament theory", which is the foundation of our modern understanding of muscle mechanics. In 1960 he became head of the Department of Physiology at University College London. He was elected a Fellow of the Royal Society in 1955, and President in 1980. The Royal Society awarded him the Copley Medal in 1973 for his collective contributions to the understanding of nerve impulses and muscle contraction. He was conferred a Knight Bachelor by the Queen in 1974, and was appointed to the Order of Merit in 1983. He was a fellow of Trinity College, Cambridge, until his death. Huxley family Huxley was born in Hampstead, London, England, on 22 November 1917. He was the youngest son of the writer and editor Leonard Huxley by Leonard Huxley's second wife Rosalind Bruce, and hence half-brother of the writer Aldous Huxley and fellow biologist Julian Huxley, and grandson of the biologist T. H. Huxley. When he was about 12, Andrew and his brother David were given a lathe by their parents.
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