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Related publications (21)

Metabolically enhanced CAR T cells efficiently clear solid tumors in mice

Chimeric antigen receptor (CAR) T cells in the solid tumor microenvironment enter a partially dysfunctional state called T cell exhaustion. Interleukin (IL)-10-producing CAR T cells retain their metabolic fitness, resist T cell exhaustion and display unpre ...

Berlin2024

Rational design of protein switches: applications in synthetic biology and cancer immunotherapy

Sailan Shui

Synthetic biology aims to engineer cells as miniature biological devices to sense, process, and respond to exogenous stimuli. Protein switches are designed to sense and respond to various molecular queues in a fast and specific manner, which fits the requi ...

EPFL2022

Optimization of operational decisions for on-demand shared mobility systems

Martin Jean Marie Joseph Repoux

This thesis introduces new operational management policies for two types of on-demand shared mobility systems, the now well-studied one-way carsharing systems and a new innovative semi-autonomous last-mile transportation system. In addition, two associated ...

EPFL2021

DESIGN OF RIDE - HAILING SERVICES FOR LARGE - SCALE SYSTEMS

Arseni Fedosseev

Today private vehicles in the cities is a high problem, due to the congestion they create, their pollution and their use of public space. Various alternatives exist, as public transportation and other modes, and still the part of people using cars remain t ...

2020

Discrete windows of feature integration

Michael Herzog, Adrien Christophe Doerig

A car drives through the night. It is hard to estimate its color from single photoreceptor activity because photoreceptor activation is short and noisy. An efficient way to estimate the color is to average photoreceptor activities along the car’s motion tr ...

SAGE PUBLICATIONS LTD2019

Is the car losing its shine? An analysis of European adolescents' imaginaries of the automobile

Vincent Kaufmann, Emmanuel Pierre Jean Ravalet, Guillaume Simon Joseph Drevon

Recent scientific publications show an increase in the average age for obtaining a driving licence. This phenomenon would tend to suggest a certain disavowal of the car among young adults and teenagers. Basing on a survey of more than 8’000 teenagers in fi ...

2019

Decoding Neural Correlates of Cognitive States to Enhance Driving Experience

José del Rocio Millán Ruiz, Ricardo Andres Chavarriaga Lozano, Huaijian Zhang, Lucian Andrei Gheorghe, Sareh Saeedi, Zahra Khaliliardali, Marija Uscumlic, Ruslan Aydarkhanov

Modern cars can support their drivers by assessing and autonomously performing different driving maneuvers based on information gathered by in-car sensors. We propose that brain–machine interfaces (BMIs) can provide complementary information that can ease ...

2018

Quantified Cars: An exploration of the position of ICT start-ups vs. car manufacturers towards digital car services and sustainable business models

Gianluigi Viscusi

In the age of digital technology cars will have to exceed their former functionality as a tool for transportation to survive as status symbols. One feasible approach is to provide valuable digital services based on car sensor data which currently is used f ...

2017

The climate impacts of feebate on cars in future scenarios

Rafael Laurenti

The ongoing EU FP7 project DYNAMIX aims to develop and assess dynamic policy mixes that achieve absolute decoupling between resource use and well-being. One of the policy instruments we assess is a feebate scheme for selected product categories. This instr ...

A World Resources Forum Production, PSI2017

Uncovering substitution patterns in new car sales using a cross nested logit model

Michel Bierlaire, Matthieu Marie Cochon de Lapparent, Anna Fernández Antolín

In the context of sales of new cars it is important to understand and model the consumers substitution patterns as well as their price elasticity towards different types of cars. To do so we develop (i) a multinomial logit model (MNL) and (ii) a cross-nest ...

2016

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