Publications associées (21)

Metabolically enhanced CAR T cells efficiently clear solid tumors in mice

Li Tang

Chimeric antigen receptor (CAR) T cells in the solid tumor microenvironment enter a partially dysfunctional state called T cell exhaustion. Interleukin (IL)-10-producing CAR T cells retain their metabolic fitness, resist T cell exhaustion and display unpre ...
Berlin2024

Rational design of protein switches: applications in synthetic biology and cancer immunotherapy

Sailan Shui

Synthetic biology aims to engineer cells as miniature biological devices to sense, process, and respond to exogenous stimuli. Protein switches are designed to sense and respond to various molecular queues in a fast and specific manner, which fits the requi ...
EPFL2022

Optimization of operational decisions for on-demand shared mobility systems

Martin Jean Marie Joseph Repoux

This thesis introduces new operational management policies for two types of on-demand shared mobility systems, the now well-studied one-way carsharing systems and a new innovative semi-autonomous last-mile transportation system. In addition, two associated ...
EPFL2021

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