Concept
Neural plate
Related publications (32)
Heterogeneity and developmental dynamics of mammalian neocortical progenitors
Gioele La Manno, Antonio Herrera Camacho, Leila Haj Abdullah Alieh
The central nervous system develops from a pool of neural progenitors which, depending on their location and time of division, generate cells committed to differentiate into specific kinds of neurons or glia. In the last decades, the developmental neurobio ...
Amsterdam2023Preparation of Single-Somite Explants from Zebrafish Embryos
Andrew Charles Oates, Sundar Ram Naganathan
The body axis of vertebrate embryos is periodically subdivided into 3D multicellular units called somites. While genetic oscillations and molecular prepatterns determine the initial length-scale of somites, mechanical processes have been implicated in sett ...
JOURNAL OF VISUALIZED EXPERIMENTS2022Towards engineering an artificial neural tube
In this thesis, I present a self-organizing neural tube organoid that is strikingly similar in morphology, cell-type composition, and patterning to the mouse embryonic neural tube. When exposed to a sequence of epiblast culture conditions and neural differ ...
EPFL2021Soft materials and technologies for neural interfaces
Implantable neural interfaces are an emerging concept which is revolutionizing various domains of medicine and rehabilitation. However, the long-term efficiency and reliability of these devices is often limited, mainly attributed to the fundamental differe ...
EPFL2021In vitro modeling of early mouse development
Previous attempts to recapitulate embryogenesis in a developmentally relevant context started with aggregates composed of a few thousand ESCs, termed embryoid bodies (EB), that upon induction of differentiation reveal a surprising level of autonomous cell ...
EPFL2020Tail Bud Progenitor Activity Relies on a Network Comprising Gdf11, Lin28, and Hox13 Genes
During the trunk-to-tail transition, axial progenitors relocate from the epiblast to the tail bud. Here, we show that this process entails a major regulatory switch, bringing tail bud progenitors under Gdf11 signaling control. Gdf11 mutant embryos have an ...
CELL PRESS2019