Concept
Reactive intermediate
Related publications (127)
Hypervalent Iodine: New Reagents and Functionalization of Peptides
Alkynes are found in a multitude of natural or synthetic bioactive compounds. In addition to the capacity of these chemical motifs to impact the physicochemical properties of a molecule of interest, the well-established reactivity of alkynes makes them ...
Impact of chlorination and ozonation of dissolved organic matter on its photo-induced production of long-lived photooxidants and excited triplet states
Urs von Gunten, Joanna Maria Houska, Silvio Canonica, Stephanie Christa Remke
Recent studies suggested that long-lived photooxidants (LLPO), which are reactive intermediates formed during irradiation of dissolved organic matter (DOM), may consist of phenoxyl radicals derived from phenolic moieties of the DOM. Besides the well-studie ...
PERGAMON-ELSEVIER SCIENCE LTD2023Activation of aminocyclopropanes via radical intermediates
Aminocyclopropanes are versatile building blocks for accessing high value-added nitrogen-containing products. To control ring-opening promoted by ring strain, the Lewis acid activation of donor-acceptor substituted systems is now well established. Over the ...
2022In situ spectroelectrochemical probing of CO redox landscape on copper single-crystal surfaces
Electrochemical reduction of CO(2) to value-added chemicals and fuels is a promising strategy to sustain pressing renewable energy demands and to address climate change issues. Direct observation of reaction intermediates during the CO(2) reduction reactio ...
NATL ACAD SCIENCES2022Organic Chemistry and Synthesis Rely More and More upon Catalysts
A few months before the COVID-19 pandemic, Pierre Vogel and Kendall N. Houk published with a new textbook Wiley-VCH, "Organic Chemistry: Theory, Reactivity, and Mechanisms in Modern Synthesis", with a foreword from the late Roberts H. Grubbs. The book demo ...
MDPI2022Photochemical oxidation of phenols and anilines mediated by phenoxyl radicals in aqueous solution
Urs von Gunten, Silvio Canonica, Stephanie Christa Remke
Reactive intermediates formed upon irradiation of chromophoric dissolved organic matter (CDOM) contribute to the degradation of various organic contaminants in surface waters. Besides well-studied "short-lived" photo oxidants, such as triplet state CDOM (3 ...
PERGAMON-ELSEVIER SCIENCE LTD2022Chemo- and regio-divergent access to fluorinated 1-alkyl and 1-acyl triazenes from alkynyl triazenes
Kay Severin, Nicolai Cramer, Carl Thomas Bormann, Jin Fay Tan
The 1,1,2,2-tetrafluoroethylene unit is prevalent in bioactive molecules and functional materials. Despite being in principle a straightforward strategy to access this motif, the direct tetrafluorination of alkynes involves very hazardous or inconvenient r ...
2022Molecular profiling of stem cell-derived retinal pigment epithelial cell differentiation established for clinical translation
Gioele La Manno, Alex Russell Lederer, Irina Khven
Human embryonic stem cell-derived retinal pigment epithelial cells (hESC-RPE) are a promising cell source to treat age-related macular degeneration (AMD). Despite several ongoing clinical studies, a detailed mapping of transient cellular states during in v ...
CELL PRESS2022Development of remote C-H bond functionalization of redox-active alcohol derivatives and oxidative transformations under photoredox catalysis
Alexandre Julien Florent Leclair
The development of radical-based remote C(sp3)-H functionalizations of redox-active alcohol derivatives, oxidative cycloaddition and rearrangement transformations under visible light photocatalysis constitute the basis of this thesis.The first chapter desc ...
EPFL2021Aqueous-phase reactive species formed by fine particulate matter from remote forests and polluted urban air
Andrea Mario Arangio, Ting Zhang, Jing Li
In the aqueous phase, fine particulate matter can form reactive species (RS) that influence the aging, properties, and health effects of atmospheric aerosols. In this study, we explore the RS yields of aerosol samples from a remote forest (Hyytiala, Finlan ...
2021