Concept

Inclusion body myositis

Related publications (12)

Cyclo His-Pro Attenuates Muscle Degeneration in Murine Myopathy Models

Johan Auwerx, Xiaoxu Li, Tanes Imamura de Lima, Keno Strotjohann, Alessia De Masi

Among the inherited myopathies, a group of muscular disorders characterized by structural and metabolic impairments in skeletal muscle, Duchenne muscular dystrophy (DMD) stands out for its devastating progression. DMD pathogenesis is driven by the progress ...

Wiley2024

Type I IFNs link skin-associated dysbiotic commensal bacteria to pathogenic inflammation and angiogenesis in rosacea

Alessio Mylonas, Yichen Wang, Jiaqi Chen

Rosacea is a common chronic inflammatory skin disease with a fluctuating course of excessive inflammation and apparent neovascularization. Microbial dysbiosis with a high density of Bacillus oleronius and increased activity of kallikrein 5, which cleaves c ...

AMER SOC CLINICAL INVESTIGATION INC2023

Molecular Regulation of Muscle Stem Cell Fate during Skeletal Muscle Regeneration and Aging

Sara Ancel

Muscle stem cells (MuSCs) are the primary source of myogenic progenitors during muscle repair and are essential for the long-term regenerative capacity of skeletal muscle. Following myofiber injury, MuSCs transition from a quiescent to an activated state, ...

EPFL2022

Assessment of idiopathic inflammatory myopathy using a deep learning method for muscle T2 mapping segmentation

Qian Wang, Tobias Kober, Tom Hilbert, Yao Zhang, Yubo Zhao

Objective To investigate the utility of an automatic deep learning (DL) method for segmentation of T2 maps in patients with idiopathic inflammatory myopathy (IIM) against healthy controls, and also the association of quantitative T2 values in patients with ...

SPRINGER2022

Enhancing mitochondrial quality control to fight neuromuscular degeneration in aging and disease

Mario Romani

Loss of mitochondrial function and proteostasis typify aging and age-associated degenerative disorders such as Alzheimer's disease and muscle aging. To date, no cure or preventive measure is available to manage these conditions. Alterations of cellular pro ...

EPFL2021

Deep learning for the rapid automatic quantification and characterization of rotator cuff muscle degeneration from shoulder CT datasets

Alexandre Terrier, Alain Farron, Elham Taghizadeh, Philippe Büchler

Objectives This study aimed at developing a convolutional neural network (CNN) able to automatically quantify and characterize the level of degeneration of rotator cuff (RC) muscles from shoulder CT images including muscle atrophy and fatty infiltration. M ...

SPRINGER2020

Inflammation clues in STING protein structure

Andrea Ablasser

The STING protein aids intracellular defences by triggering inflammation. Studies that uncover how STING is activated might lead to strategies for targeting this protein in the treatment of cancer or autoimmune diseases. ...

NATURE PUBLISHING GROUP2019

EMG Pattern Recognition Using Decomposition Techniques for Constructing Multiclass Classifiers

Christian Enz, Claudio Bruschini, Huaiqi Huang, Tao Li, Jörn Justiz

To improve the dexterity of multi-functional myoelectric prosthetic hand, more accurate hand gesture recognition based on surface electromyographic (sEMG) signal is needed. This paper evaluates two types of time-domain EMG features, one independent feature ...

IEEE2016

Repeated Double-Poling Sprint Training in Hypoxia by Competitive Cross-country Skiers

Jean-Marc Vesin, Grégoire Millet

Purpose Repeated-sprint training in hypoxia (RSH) was recently shown to improve repeated-sprint ability (RSA) in cycling. This phenomenon is likely to reflect fiber type-dependent, compensatory vasodilation, and therefore, our hypothesis was that RSH is ev ...

Lippincott Williams & Wilkins2015

Assessing dystrophies and other muscle diseases at the nanometer scale by atomic force microscopy

Giovanni Dietler, Harald Brune, Andrzej Kulik, Nicolas Mermod, Guillaume Witz, Stefania Puttini

Aim: Atomic force microscopy nanoindentation of myofibers was used to assess and quantitatively diagnose muscular dystrophies from human patients. Materials & methods: Myofibers were probed from fresh or frozen muscle biopsies from human dystrophic patient ...

Future Medicine2014

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