Loïc Vivien FumeauxLoïc Fumeaux was born in 1978 in Geneva. After a scientific degree, he joined the EPFL . He graduated as an architect in 2007 under the direction of Professors Jean- Paul Jaccaud and Bruno Marchand. His master's thesis was about sustainability integration from urban scale to the architectural details. This masters project was awarded with the SIA Prize and the Construction and sustainable development Prize (BG Ingénieurs Conseils).
In addition to his studies, Loïc develops independant activities and collaborated with LVBK Rotterdam and Lacroix- Chessex Geneva. In 2009 , he founded xy-ar.ch with Amélie Poncety . The office participates in many competitions and won the competition for the redevelopment of the Place de la Planta in Sion , currently under development .
In 2010, he became studio assistant at the LAST (Laboratory of architecture and sustainable technologies) headed by Prof. Emmanuel Rey. After a period dedicated to teaching he starts a PhD focused on the integration of sustainability criteria into the design process of temporary event infrastructures .
He is a member of the group of architects at SIA section Vaud and Treasurer of InterAssAr.
Henry MarkramHenry Markram started a dual scientific and medical career at the University of Cape Town, in South Africa. His scientific work in the 80s revealed the polymodal receptive fields of pontomedullary reticular formation neurons in vivo and how acetylcholine re-organized these sensory maps.
He moved to Israel in 1988 and obtained his PhD at the Weizmann Institute where he discovered a link between acetylcholine and memory mechanisms by being the first to show that acetylcholine modulates the NMDA receptor in vitro studies, and thereby gates which synapses can undergo synaptic plasticity. He was also the first to characterize the electrical and anatomical properties of the cholinergic neurons in the medial septum diagonal band.
He carried out a first postdoctoral study as a Fulbright Scholar at the NIH, on the biophysics of ion channels on synaptic vesicles using sub-fractionation methods to isolate synaptic vesicles and patch-clamp recordings to characterize the ion channels. He carried out a second postdoctoral study at the Max Planck Institute, as a Minerva Fellow, where he discovered that individual action potentials propagating back into dendrites also cause pulsed influx of Ca2 into the dendrites and found that sub-threshold activity could also activated a low threshold Ca2 channel. He developed a model to show how different types of electrical activities can divert Ca2 to activate different intracellular targets depending on the speed of Ca2 influx an insight that helps explain how Ca2 acts as a universal second messenger. His most well known discovery is that of the millisecond watershed to judge the relevance of communication between neurons marked by the back-propagating action potential. This phenomenon is now called Spike Timing Dependent Plasticity (STDP), which many laboratories around the world have subsequently found in multiple brain regions and many theoreticians have incorporated as a learning rule. At the Max-Planck he also started exploring the micro-anatomical and physiological principles of the different neurons of the neocortex and of the mono-synaptic connections that they form - the first step towards a systematic reverse engineering of the neocortical microcircuitry to derive the blue prints of the cortical column in a manner that would allow computer model reconstruction.
He received a tenure track position at the Weizmann Institute where he continued the reverse engineering studies and also discovered a number of core principles of the structural and functional organization such as differential signaling onto different neurons, models of dynamic synapses with Misha Tsodyks, the computational functions of dynamic synapses, and how GABAergic neurons map onto interneurons and pyramidal neurons. A major contribution during this period was his discovery of Redistribution of Synaptic Efficacy (RSE), where he showed that co-activation of neurons does not only alter synaptic strength, but also the dynamics of transmission. At the Weizmann, he also found the tabula rasa principle which governs the random structural connectivity between pyramidal neurons and a non-random functional connectivity due to target selection. Markram also developed a novel computation framework with Wolfgang Maass to account for the impact of multiple time constants in neurons and synapses on information processing called liquid computing or high entropy computing.
In 2002, he was appointed Full professor at the EPFL where he founded and directed the Brain Mind Institute. During this time Markram continued his reverse engineering approaches and developed a series of new technologies to allow large-scale multi-neuron patch-clamp studies. Markrams lab discovered a novel microcircuit plasticity phenomenon where connections are formed and eliminated in a Darwinian manner as apposed to where synapses are strengthening or weakened as found for LTP. This was the first demonstration that neural circuits are constantly being re-wired and excitation can boost the rate of re-wiring.
At the EPFL he also completed the much of the reverse engineering studies on the neocortical microcircuitry, revealing deeper insight into the circuit design and built databases of the blue-print of the cortical column. In 2005 he used these databases to launched the Blue Brain Project. The BBP used IBMs most advanced supercomputers to reconstruct a detailed computer model of the neocortical column composed of 10000 neurons, more than 340 different types of neurons distributed according to a layer-based recipe of composition and interconnected with 30 million synapses (6 different types) according to synaptic mapping recipes. The Blue Brain team built dozens of applications that now allow automated reconstruction, simulation, visualization, analysis and calibration of detailed microcircuits. This Proof of Concept completed, Markrams lab has now set the agenda towards whole brain and molecular modeling.
With an in depth understanding of the neocortical microcircuit, Markram set a path to determine how the neocortex changes in Autism. He found hyper-reactivity due to hyper-connectivity in the circuitry and hyper-plasticity due to hyper-NMDA expression. Similar findings in the Amygdala together with behavioral evidence that the animal model of autism expressed hyper-fear led to the novel theory of Autism called the Intense World Syndrome proposed by Henry and Kamila Markram. The Intense World Syndrome claims that the brain of an Autist is hyper-sensitive and hyper-plastic which renders the world painfully intense and the brain overly autonomous. The theory is acquiring rapid recognition and many new studies have extended the findings to other brain regions and to other models of autism.
Markram aims to eventually build detailed computer models of brains of mammals to pioneer simulation-based research in the neuroscience which could serve to aggregate, integrate, unify and validate our knowledge of the brain and to use such a facility as a new tool to explore the emergence of intelligence and higher cognitive functions in the brain, and explore hypotheses of diseases as well as treatments.
David Atienza AlonsoDavid Atienza Alonso is an associate professor of EE and director of the Embedded Systems Laboratory (ESL) at EPFL, Switzerland. He received his MSc and PhD degrees in computer science and engineering from UCM, Spain, and IMEC, Belgium, in 2001 and 2005, respectively. His research interests include system-level design methodologies for multi-processor system-on-chip (MPSoC) servers and edge AI architectures. Dr. Atienza has co-authored more than 350 papers, one book, and 12 patents in these previous areas. He has also received several recognitions and award, among them, the ICCAD 10-Year Retrospective Most Influential Paper Award in 2020, Design Automation Conference (DAC) Under-40 Innovators Award in 2018, the IEEE TCCPS Mid-Career Award in 2018, an ERC Consolidator Grant in 2016, the IEEE CEDA Early Career Award in 2013, the ACM SIGDA Outstanding New Faculty Award in 2012, and a Faculty Award from Sun Labs at Oracle in 2011. He has also earned two best paper awards at the VLSI-SoC 2009 and CST-HPCS 2012 conference, and five best paper award nominations at the DAC 2013, DATE 2013, WEHA-HPCS 2010, ICCAD 2006, and DAC 2004 conferences. He serves or has served as associate editor of IEEE Trans. on Computers (TC), IEEE Design & Test of Computers (D&T), IEEE Trans. on CAD (T-CAD), IEEE Transactions on Sustainable Computing (T-SUSC), and Elsevier Integration. He was the Technical Program Chair of DATE 2015 and General Chair of DATE 2017. He served as President of IEEE CEDA in the period 2018-2019 and was GOLD member of the Board of Governors of IEEE CASS from 2010 to 2012. He is a Distinguished Member of ACM and an IEEE Fellow.
Marilyne AndersenMarilyne Andersen is a Full Professor of Sustainable Construction Technologies and heads the Laboratory of Integrated Performance in Design (LIPID) that she launched in the Fall of 2010. She was Dean of the School of Architecture, Civil and Environmental Engineering (ENAC) at EPFL from 2013 to 2018 and is the Academic Director of the Smart Living Lab in Fribourg. She also co-leads the Student Kreativity and Innovation Laboratory (SKIL) at ENAC. Before joining EPFL as a faculty, she was an Assistant Professor then Associate Professor tenure-track in the Building Technology Group of the MIT School of Architecture and Planning and the Head of the MIT Daylighting Lab that she founded in 2004. She has also been Invited Professor at the Singapore University of Technology and Design in 2019. Marilyne Andersen owns a Master of Science in Physics and specialized in daylighting through her PhD in Building Physics at EPFL in the Solar Energy and Building Physics Laboratory (LESO) and as a Visiting Scholar in the Building Technologies Department of the Lawrence Berkeley National Laboratory in California. Her research lies at the interface between science, engineering and architectural design with a dedicated emphasis on the impact of daylight on building occupants. Focused on questions of comfort, perception and health and their implications on energy considerations, these research efforts aim towards a deeper integration of the design process with daylighting performance and indoor comfort, by reaching out to various fields of science, from chronobiology and neuroscience to psychophysics and computer graphics. She is leveraging this research in practice through OCULIGHT dynamics, a startup company she co-founded, which offers specialized consulting services on daylight performance and its psycho-physiological effects on building occupants. She is the author of more than 200 papers published in peer-reviewed journals and international conferences and the recipient of several grants and awards including: the Daylight Award for Research (2016), eleven publication awards and distinctions (2009, 2011, 2012, 2015, 2018, 2019) including the Taylor Technical Talent Award 2009 granted by the Illuminating Engineering Society, the 3M Non-Tenured Faculty Grant (2009), the Mitsui Career Development Professorship at MIT (2008) and the EPFL prize of the Chorafas Foundation awarded to her PhD thesis in Sustainability (2005). Her research or teaching has been supported by professional, institutional and industrial organizations such as: the Swiss and the U.S. National Science Foundations, the Velux Foundation, the European Horizon 2020 program, the Boston Society of Architects, the MIT Energy Initiative and InnoSuisse. She was the leader and faculty advisor of the Swiss Team and its NeighborHub project, who won the U.S. Solar Decathlon 2017 competition with 8 podiums out of 10 contests. She is a member of the Board of the LafargeHolcim Foundation for Sustainable Construction and Head of its Academic Committee. She is also a member of the Editorial Board of the journal Building and Environment by Elsevier, and of the journals LEUKOS (of the Illuminating Engineering Society) and Buildings and Cities, by Taylor and Francis. She is expert to the Innovation Council of InnoSuisse and Founding member as well as Board member of the Foundation Culture du Bâti (CUB), and is also founding member of the Daylight Academy and an active member of several committees of the Illuminating Engineering Society (IES) and International Commission on Illumination (CIE).
Peter RyserDr. Peter Ryser is a Professor Emeritus at the Swiss Federal Institute of Technology in Lausanne. He has over three decades of research and teaching experience from various corporate and academic institutions. He was previously a Director at Siemens Building Technologies where he was responsible for R&D, product innovation and patents. Dr. Ryser has a Ph.D. in applied Physics from the University of Geneva, a Masters degree in Experimental Physics and an MBA.
Vincent Pierre LamirandAfter a PhD on the measurement of (p,n) reactions cross sections on small accelerators (IRSN, France), I have worked on the development of neutron detectors and measurement methods for reactor physics (CEA, France). I am part of the LRS staff since October 2014.
André SchiperAndré Schiper graduated in Physics from the ETHZ in Zurich in 1973 and received the PhD degree in Computer Science from EPFL in 1980. He has been a professor of computer science at EPFL since 1985, leading the Distributed Systems Laboratory. During the academic year 1992-1993 he was on sabbatical leave at the University of Cornell, Ithaca, New York (working with Ken Birman and Aleta Ricciardi), and in 2004-2005 at the Ecole Polytechnique in Palaiseau, France (working with Bernadette Charron-Bost). His research interests are in the area of dependable distributed systems, middleware support for dependable systems, replication techniques (including for database systems), group communication, distributed transactions, and MANETs (mobile ad-hoc networks).
Prof. Schiper is member of the editorial boards of
Distributed Computing (DC), Springer Verlag - ACM,
Transactions on Dependable and Secure Computing (TDSC), IEEE,
International Journal of Security and Networks (Inderscience).
