Concept

Keloid

Related publications (7)

Engineering the Extra Domain A of fibronectin as a vaccine adjuvant and study of its role in tissue regeneration

The extracellular matrix (ECM) protein fibronectin (FN) is a remarkably multifaceted molecule, including numerous fibronectin type III (FNIII) repeats carrying out different functions, which despite being extensively studied for over thirty years still pre ...

EPFL2016

Epiphyseal chondro-progenitors provide a stable cell source for cartilage cell therapy

Dominique Pioletti, Corinne Scaletta, Salim Elias Darwiche

Articular cartilage regeneration poses particularly tough challenges for implementing cell-‐based therapies. Many cell types have been investigated looking for a balanced combination of responsiveness and stability, yet techniques are still far from defin ...

2012

Regulation of myofibroblast activities: Calcium pulls some strings behind the scene

Boris Hinz, Lysianne Follonier Castella

Myofibroblast-induced remodeling of collagenous extracellular matrix is a key component of our body's strategy to rapidly and efficiently repair damaged tissues; thus myofibroblast activity is considered crucial in assuring the mechanical integrity of vita ...

Elsevier2010

Coordination of Myofibroblast Contraction in Vitro

Lysianne Follonier Castella

The aim of this thesis is to elucidate the common mechanisms that regulate myofibroblast contraction and intercellular communication, with a particular focus on the role of Ca2+ signalling. Synthesis and remodelling of collagenous matrix by myofibroblasts ...

EPFL2010

Mechanical orchestration of tissue remodeling

Pierre Jean Arnould Wipff

After organ injury, a complex sequence of events is triggered to heal the tissue and to form a scar. Myofibroblasts, specialized contractile and secretory fibroblasts, are one of the many cell types that participate in the remodeling process. Myofibroblast ...

EPFL2008

On the in-series and in-parallel contribution of elastin assessed by a structure-based biomechanical model of the arterial wall

Nikolaos Stergiopoulos, Sylvain Roy, Alkiviadis Tsamis, Gilles Prod'Hom

Earlier experimental work on decellularized arteries revealed the existence of significant residual stresses within the arterial wall, which are released upon chemical removal of vascular smooth muscle in normal arteries causing substantial radial expansio ...

2008

Clinical photodynamic therapy for superficial cancer in the esophagus and the bronchi: 514 nm compared with 630 nm light irradiation after sensitization with Photofrin II

Hubert van den Bergh, Georges Wagnières

Photodynamic therapy (PDT) for cancer in the esophagus and bronchi with red (630 nm) light may occasionally lead to wall perforation and fistula. Therefore, the clin. use of a less penetrating wavelength (514 nm) was investigated for the curative treatment ...

1998

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