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New 2-(aminomethyl)-5-(hydroxymethyl)pyrrolidine-3,4-diol derivatives were synthesized from (5S)-5-[(trityloxy)methyl]pyrrolidin-2-one (6) (Schemes 1 and 2) and their inhibitory activities toward 25 glycosidases assayed (Table). The influence of the config ...
To find a configuration of a distributed system satisfying performance goals is a complex search problem that involves many design parameters, like hardware selection, job distribution and process configuration. Performance models are a powerful tools to a ...
A key problem in current sensor network technology is the heterogeneity of the available software and hardware platforms which makes deployment and application development a tedious and time consuming task. To minimize the unnecessary and repetitive implem ...
In this paper we present the design and evaluate the performance of an autonomic workflow execution engine. Although there exist many distributed workflow engines, in practice, it remains a difficult problem to deploy such systems in an optimal configurati ...
This paper presents a thermal flow sensor based on the calorimetric principle realized by using low temperature co-fired ceramic (LTCC) technology, where the tapes and flow channel have been structured by laser machining. A standard configuration of a calo ...
A numerical model of the medial open wedge tibial osteotomy based on the finite element method was developed. Two plate positions were tested numerically. In a configuration, (a), the plate was fixed in a medial position and (b) in an anteromedial position ...
Semiconductor-metal hybrid structures can show a large magnetoresistance effect, the extraordinary magnetoresistance (EMR) effect. In this work, we study theoretically the influence of the voltage probe configuration on the magnetoresistance of such hybrid ...
Moving from the observation that drainage network configurations minimizing total energy dissipation are stationary solutions of the general equation describing landscape evolution, we review theoretical and observational evidence on river patterns and the ...
Injection locking of two DFB semiconductors opens new possibilities to generate effective signals for fibre sensing. This is illustrated through the application to distributed Brillouin sensing that shows significant progress with respect to established te ...
The structural and thermodn. properties of a 6-residue β-peptide I that was designed to form a hairpin conformation have been studied by NMR spectroscopy and mol. dynamics simulation in methanol soln. The predicted hairpin would be characterized by a 10-me ...
