Concept

Biological psychiatry

Related publications (10)

Glucocorticoid-based pharmacotherapies preventing PTSD

Maria del Carmen Sandi Perez, Silvia Monari

Posttraumatic stress disorder (PTSD) is a highly disabling psychiatric condition that may arise after exposure to acute and severe trauma. It is a highly prevalent mental disorder worldwide, and the current treatment options for these patients remain limit ...

PERGAMON-ELSEVIER SCIENCE LTD2023

Neurotrophic-mimetic strategy to rescue synaptic plasticity and cognitive functions in a mouse model of Down syndrome

Diego Ghezzi

Down syndrome (DS) is caused by the triplication of human chromosome 21, and it is the most frequent genetic cause of cognitive disabilities. Although numerous studies have shown that cognitive impairment possibly arises from dysfunction of the hippocampal ...

2018

Solar photo-Fenton and UV/H2O2 processes against the antidepressant Venlafaxine in urban wastewaters and human urine. Intermediates formation and biodegradability assessment

Hubert Girault, César Pulgarin, Dominique Grandjean, Luiz Felippe De Alencastro, Stefanos Giannakis, Milica Jovic, Idriss Hendaoui

In this work, the use of Advanced Oxidation Processes (AOPs) against the degradation of an emerging contaminant has been subjected under systematic investigation. The optimization of treatment of the anti- depressant drug Venlafaxine (VFA) was performed, u ...

Elsevier Science Sa2017

Computational methods and modeling of cellular function for the optimization of protein production and the study of cellular disease states

Joana Raquel Pinto Vieira

Systems biology is a multidisciplinary field that weaves together all the basic sciences through the use of computational and bioinformatics tools, to provide a more integrative view of the complex molecular interactions taking place within and among cells ...

EPFL2017

Targeting Treatment-Resistant Auditory Verbal Hallucinations in Schizophrenia with fMRI-Based Neurofeedback - Exploring Different Cases of Schizophrenia

Yury Koush

Auditory verbal hallucinations (AVHs) are a hallmark of schizophrenia and can significantly impair patients' emotional, social, and occupational functioning. Despite progress in psychopharmacology, over 25% of schizophrenia patients suffer from treatment-r ...

Frontiers Media Sa2016

N-acetylcysteine normalizes neurochemical changes in the glutathione-deficient schizophrenia mouse model during development

Rolf Gruetter, João Miguel das Neves Duarte, Kim Do

Background: Glutathione (GSH) is the major cellular redox-regulator and antioxidant. Redox-imbalance due to genetically impaired GSH synthesis is among the risk factors for schizophrenia. Here we used a mouse model with chronic GSH deficit induced by knock ...

2012

Controversy: Noninvasive and invasive cortical stimulation show efficacy in treating stroke patients

Friedhelm Christoph Hummel

Stroke is the leading cause of disability in the adult population of western industrialized countries. Despite significant improvements of acute stroke care, two thirds of stroke survivors have to cope with persisting neurologic deficits. Adjuvant brain st ...

2008

Joint co-clustering: Co-clustering of genomic and clinical bioimaging data

Giovanni De Micheli, Luca Benini

For better understanding the genetic mechanisms underlying clinical observations, and better defining a group of potential candidates for protein-family-inhibiting therapy, it is interesting to determine the correlations between genomic, clinical data and ...

Elsevier2008

Finding Co-Clusters of Genes and Clinical Parameters

Giovanni De Micheli, Luca Benini

For better understanding of genetic mechanisms underlying clinical observations, we often want to determine which genes and clinical traits are interrelated. We introduce a computational method that can find co-clusters or groups of genes and clinical para ...

2005

Dog phobia in a motion-blind patient

Olaf Blanke

INTRODUCTION: A prominent neurophysiological model of phobia generation holds that specific phobia might result from the uncoupling of unaware subcortical fear responses from aware cortical fear responses. Former responses are thought to be automatic and f ...

Taylor & Francis2003

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