Concept

Generalized estimating equation

Summary
In statistics, a generalized estimating equation (GEE) is used to estimate the parameters of a generalized linear model with a possible unmeasured correlation between observations from different timepoints. Although some believe that Generalized estimating equations are robust in everything even with the wrong choice of working-correlation matrix, Generalized estimating equations are only robust to loss of consistency with the wrong choice. Regression beta coefficient estimates from the Liang Zeger GEE are consistent, unbiased, asymptotically normal even when the working correlation is misspecified, under mild regularity conditions. GEE is higher in efficiency than generalized linear iterative model GLIM (software) in the presence of high autocorrelation. When the true working-correlation is known, consistency does not require MCAR. Huber-White standard errors improve the efficiency of Liang Zeger GEE in the absence of serial Autocorrelation but may
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