Fréjus | EPFL Graph Search

Fréjus (fʁeʒys; Frejús fɾeˈdʒys) is a commune in the Var department in the Provence-Alpes-Côte d'Azur region in Southeastern France. In 2019, it had a population of 54,458. It neighbours Saint-Raphaël, effectively forming one urban agglomeration. The north of the commune forms part of the Massif de l'Esterel. On 2 December 1959, the Malpasset Dam, on the Reyran River above the city of Fréjus, ruptured, killing over 400 people. The origins of Frejus probably lie with the Celto-Ligurian people who settled around the natural harbour of Aegytna. The remains of a defensive wall are still visible on Mont Auriasque and Cap Capelin. The Phocaeans of Marseille later established an outpost on the site. Frejus was strategically situated at an important crossroads formed by the Via Julia Augusta (which ran between Italy and the Rhône) and the Via Domitia. Although there are only few traces of a settlement at that time, it is known that the poet Cornelius Gallus was born there in 67 BC. Julius Caesar wanted to supplant Massalia and he founded the city as Forum Julii meaning 'market of Julius'. Tacitus also named its port claustra maris (gateway to sea). The exact date of the founding of Forum Julii is uncertain, but it was certainly before 43 BC since it appears in the correspondence between Plancus and Cicero and 49 BC is most likely. It was at Forum Julii that Octavius repatriated the galleys taken from Mark Antony at the Battle of Actium in 31 BC. Between 29 and 27 BC, it became a colony for his veterans of the 8th legion, adding the suffix Octavanorum Colonia. Augustus made the city the capital of the new province of Narbonensis in 22 BC, spurring rapid development. It became one of the most important ports in the Mediterranean; its port was the only naval base for the Roman fleet of Gaul which remained operative until the reign of Claudius and only the second port after Ostia until at least the time of Nero. Subsequently, under Tiberius, the major monuments and amenities still visible today were constructed: the amphitheatre, the aqueduct, the lighthouse, the baths and the theatre.

Phosphorylation of the VAR2CSA extracellular region is associated with enhanced adhesive properties to the placental receptor CSA

Romain Hamelin, Florence Armand, Marc Moniatte

Plasmodium falciparum is the main cause of disease and death from malaria. P. falciparum virulence resides in the ability of infected erythrocytes (IEs) to sequester in various tissues through the interaction between members of the polymorphic P. falciparu ...

PUBLIC LIBRARY SCIENCE2019