Concept

Toxicity

Related publications (93)

In vitro acute toxicity assessment of tire tread particles using rainbow trout cell lines of gill and intestine

Kristin Schirmer, Florian Frédéric Vincent Breider, Benoît Jean Dominique Ferrari, Thibault Béranger Masset

Tire and road wear particles (TRWP) are generated by the abrasion of tires while driving, and recent questions were raised in regards to their potential contribution to microplastics released into the aquatic environment and their potential toxicological i ...

2021

Predicting exposure concentrations of chemicals with a wide range of volatility and hydrophobicity in different multi-well plate set-ups

Kristin Schirmer, Julita Maria Stadnicka-Michalak

Quantification of chemical toxicity in small-scale bioassays is challenging owing to small volumes used and extensive analytical resource needs. Yet, relying on nominal concentrations for effect determination maybe erroneous because loss processes can sign ...

NATURE RESEARCH2021

Probiotics and gut microbiome-Prospects and challenges in remediating heavy metal toxicity

Edgard Gnansounou, Ranjna Sirohi

The gut microbiome, often referred to as "super organ", comprises up to a hundred trillion microorganisms, and the species diversity may vary from person to person. They perform a decisive role in diverse biological functions related to metabolism, immunit ...

ELSEVIER2021

Extending the Concept of Predicting Fish Acute Toxicity In Vitro to the Intestinal Cell Line RTgutGC

Kristin Schirmer, Hannah Inka Schug, Jenny Maner

Testing chemicals for fish acute toxicity is a legal requirement in many countries as part of environmental risk assessment. To reduce the number of fish used, substantial efforts have been focused on alternative approaches. Prominently, the cell viability ...

SPEKTRUM AKADEMISCHER VERLAG-SPRINGER-VERLAG GMBH2020

The impact of synthetic amorphous silica (E 551) on differentiated Caco-2 cells, a model for the human intestinal epithelium

Heinrich Hofmann

For several decades, food-grade synthetic amorphous silica (SAS) have been used as a technological additive to reduce caking of food powders. Human exposure is thus inevitable and safety concerns are taken seriously. The toxicity of silica in general and S ...

PERGAMON-ELSEVIER SCIENCE LTD2020

Subcellular Chemical Imaging: New Avenues in Cell Biology

Melissa Kathleen Passarelli

To better understand the physiology and acclimation capability of the cell, one of the great challenges of the future is to access the interior of a cell and unveil its chemical landscape (composition and distribution of elements and molecules). Chemical i ...

ELSEVIER SCIENCE LONDON2020

Volatile organic compounds in 169 energy-efficient dwellings in Switzerland

Dusan Licina, Shen Yang

Exposure to elevated levels of certain volatile organic compounds (VOCs) in households has been linked to deleterious health effects. This study presents the first large-scale investigation of VOC levels in 169 energy-efficient dwellings in Switzerland. Th ...

2020

Comparison of the impact of ozone, chlorine dioxide, ferrate and permanganate pre-oxidation on organic disinfection byproduct formation during post-chlorination

Urs von Gunten

Pre-oxidation is commonly used to mitigate the formation of byproducts during post-disinfection. A comparative study of the impact of four pre-oxidants, ozone (O-3), chlorine dioxide (ClO2), permanganate (Mn(vii)) and ferrate (Fe(vi)), on the formation of ...

ROYAL SOC CHEMISTRY2020

MIL-101(Fe)/g-C3N4 for enhanced visible-light-driven photocatalysis toward simultaneous reduction of Cr(VI) and oxidation of bisphenol A in aqueous media

Kevin Sivula, Nestor Guijarro Carratala, Yongpeng Liu, Feiping Zhao

Heterostructured composites with an excellent photocatalytic activity have attracted increasing attention because of their great application in environmental remediation. Herein, a MIL-101(Fe)/g-C3N4 heterojunction was synthesized via in-situ growth of MIL ...

ELSEVIER2020

A fish intestinal barrier model to assess the interaction with chemicals in vitro

Hannah Inka Schug

The intestinal epithelium acts as vital gate keeper between the fish and its surrounding environment. A single layer of connected epithelial cells forms a selective barrier, which, among other essential functions, is important for nutrient uptake and defen ...

EPFL2019

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