Publications related to Intravenous therapy

A Fast pH-Switchable and Self-Healing Supramolecular Hydrogel Carrier for Guided, Local Catheter Injection in the Infarcted Myocardium

Maartje Martina Cornelia Bastings

Minimally invasive intervention strategies after myocardial infarction use state-of-the-art catheter systems that are able to combine mapping of the infarcted area with precise, local injection of drugs. To this end, catheter delivery of drugs that are not ...

Wiley-VCH Verlag2013

Prevention of Caval Collapse During Venous Drainage for CPB

Julien Favre

A new plastic self-expanding Smartcanula (Smartcanula LLC, Lausanne, Switzerland) is designed for central insertion and prevention of caval collapse. The objective of our work is to assess the influence of the new design on atrial chatter. Caval collapse o ...

Lippincott Williams & Wilkins2013

New Evidence of Neuroprotection by Lactate after Transient Focal Cerebral Ischaemia: Extended Benefit after Intracerebroventricular Injection and Efficacy of Intravenous Administration

Pierre Magistretti, Ximena Castillo

Background: Lactate protects mice against the ischaemic damage resulting from transient middle cerebral artery occlusion (MCAO) when administered intracerebroventricularly at reperfusion, yielding smaller lesion sizes and a better neurological outcome 48 h ...

Karger2012

In vivo real-time metabolic studies in mice at physiological concentrations following 1-13C lactate injection

Rolf Gruetter, Mor-Miri Mishkovsky, Tian Cheng, Arnaud Comment, Yuhei Takado

The real-time metabolic transformation of lactate in the mouse head was monitored following the injection of hyperpolarized 1-13C lactate at physiological doses. The results were compared with metabolic studies performed with hyperpolarized 1-13C pyruvate ...

2012

Fluorine-19 Magnetic Resonance Angiography of the Mouse

Yves Pilloud, Ruud van Heeswijk

Purpose: To implement and characterize a fluorine-19 (F-19) magnetic resonance imaging (MRI) technique and to test the hypothesis that the F-19 MRI signal in steady state after intravenous injection of a perfluoro-15-crown-5 ether (PCE) emulsion may be exp ...

Public Library of Science2012

Improving Protein Pharmacokinetics by Engineering Erythrocyte Affinity

Stephane Kontos, Jeffrey Alan Hubbell

Poor pharmacokinetic profiles are often the underlying reason for the failure of novel protein drugs to reach clinical translation. Current passive half-life improvement methods focus on increasing the apparent hydrodynamic radius of the drug. We sought to ...

American Chemical Society2010

Photodynamic therapy induces selective extravasation of macromolecules: Insights using intravital microscopy

Hubert van den Bergh, Elodie Debefve

Photodynamic therapy (PDT) with Visudyne acts by direct cellular phototoxicity and/or by an indirect vascular-mediated effect. Here, we demonstrate that the vessel integrity interruption by PDT can promote the extravasation of a macromolecular agent in nor ...

Elsevier2010

Processing of fluorescence angiograms for the quantification of vascular effects induced by anti-angiogenic agents in the CAM model

Hubert van den Bergh, Georges Wagnières, Patrycja Nowak-Sliwinska

The chicken embryo chorioallantoic membrane (CAM) is widely used as an in vivo model to study the vascular effects of angiogenesis modulating agents. The main goal of the present study was to develop and validate a quantitative method to characterize time- ...

Elsevier2010

Vascular effects induced by anti-VEGF agents in the CAM model: Effect of the DMSO

Hubert van den Bergh, Georges Wagnières, Patrycja Nowak-Sliwinska

The chicken embryo's chorioallantoic membrane (CAM) is widely used as an in vivo model to study the vascular effects induced by agents administrated topically or intravenously. Hence, in the vascular plexus of this respiratory membrane, angiogenic and anti ...

2009

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Intravenous therapy

A Fast pH-Switchable and Self-Healing Supramolecular Hydrogel Carrier for Guided, Local Catheter Injection in the Infarcted Myocardium

Prevention of Caval Collapse During Venous Drainage for CPB

New Evidence of Neuroprotection by Lactate after Transient Focal Cerebral Ischaemia: Extended Benefit after Intracerebroventricular Injection and Efficacy of Intravenous Administration

In vivo real-time metabolic studies in mice at physiological concentrations following 1-13C lactate injection

Fluorine-19 Magnetic Resonance Angiography of the Mouse

Development of a novel biomaterial for drug delivery

Improving Protein Pharmacokinetics by Engineering Erythrocyte Affinity

Photodynamic therapy induces selective extravasation of macromolecules: Insights using intravital microscopy

Processing of fluorescence angiograms for the quantification of vascular effects induced by anti-angiogenic agents in the CAM model

Vascular effects induced by anti-VEGF agents in the CAM model: Effect of the DMSO

Graph Chatbot

Chat with Graph Search

A Fast pH-Switchable and Self-Healing Supramolecular Hydrogel Carrier for Guided, Local Catheter Injection in the Infarcted Myocardium

Prevention of Caval Collapse During Venous Drainage for CPB

In vivo real-time metabolic studies in mice at physiological concentrations following 1-13C lactate injection

New Evidence of Neuroprotection by Lactate after Transient Focal Cerebral Ischaemia: Extended Benefit after Intracerebroventricular Injection and Efficacy of Intravenous Administration

Improving Protein Pharmacokinetics by Engineering Erythrocyte Affinity

Fluorine-19 Magnetic Resonance Angiography of the Mouse

Processing of fluorescence angiograms for the quantification of vascular effects induced by anti-angiogenic agents in the CAM model

Development of a novel biomaterial for drug delivery

Photodynamic therapy induces selective extravasation of macromolecules: Insights using intravital microscopy

Vascular effects induced by anti-VEGF agents in the CAM model: Effect of the DMSO