Publications related to Lung cancer

The use of texture-based radiomics CT analysis to predict outcomes in early-stage non-small cell lung cancer treated with stereotactic ablative radiotherapy

Adrien Raphaël Depeursinge, Pierre Starkov

Objective: Stereotactic ablative radiotherapy (SABR) is being increasingly used as a non-invasive treatment for early-stage non-small cell lung cancer (NSCLC). A non-invasive method to estimate treatment outcomes in these patients would be valuable, especi ...

BRITISH INST RADIOLOGY2019

MALDI Detection of Exosomes: A Potential Tool for Cancer Studies

Hubert Girault, Horst Pick, Natalia Gasilova, Tzu-En Lin, Yingdi Zhu

Matrix-assisted laser desorption ionization time-of-flight mass spectrometry is used to detect intact whole exosomes, yielding exosomal fingerprints within minutes. This rapid exosome detection approach is proposed as a potential tool for cancer studies. M ...

2019

RasGRP1 is a potential biomarker for stratifying anti-EGFR therapy response in colorectal cancer

Mauro Delorenzi, Delphine Yvette L Grun

Colorectal cancer (CRC) is the third most frequent neoplastic disorder and is a main cause of tumor-related mortality, as many patients progress to stage IV metastatic CRC. Standard care consists of combination chemotherapy (FOLFIRI or FOLFOX). Patients wi ...

AMER SOC CLINICAL INVESTIGATION INC2019

The antimicrobial peptide defensin cooperates with tumour necrosis factor to drive tumour cell death in Drosophila

Bruno Lemaitre, Anna Dostalova

Antimicrobial peptides (AMPs) are small cationic molecules best known as mediators of the innate defence against microbial infection. While in vitro and ex vivo evidence suggest AMPs' capacity to kill cancer cells, in vivo demonstration of an anti-tumour r ...

ELIFE SCIENCES PUBLICATIONS LTD2019

Toward Microfluidic Label-Free Isolation and Enumeration of Circulating Tumor Cells from Blood Samples

Philippe Renaud, Margaux Catherine Marie Duchamp, Camille Alice Raillon, Benoît Xavier Emmanuel Desbiolles

The isolation, analysis, and enumeration of circulating tumor cells (CTCs) from cancer patient blood samples are a paradigm shift for cancer patient diagnosis, prognosis, and treatment monitoring. Most methods used to isolate and enumerate these target cel ...

WILEY2019

Adverse effects of immune-checkpoint inhibitors: epidemiology, management and surveillance

Filipe Amândio Brandão Sanches Vong Martins, Olivier Michielin

Immune-checkpoint inhibitors (ICIs), including anti-cytotoxic T lymphocyte antigen 4 (CTLA-4), anti-programmed cell death 1 (PD-1) and anti-programmed cell death 1 ligand 1 (PD-L1) antibodies, are arguably the most important development in cancer therapy o ...

NATURE PUBLISHING GROUP2019

A structure-based mechanism of cisplatin resistance mediated by glutathione transferase P1-1

Paul Joseph Dyson, Laure Menin, Wee Han Ang

Cisplatin [cis-diamminedichloroplatinum(II) (cis-DDP)] is one of the most successful anticancer agents effective against a wide range of solid tumors. However, its use is restricted by side effects and/or by intrinsic or acquired drug resistance. Here, we ...

PNAS2019

Recruitment of CD103(+) dendritic cells via tumor-targeted chemokine delivery enhances efficacy of checkpoint inhibitor immunotherapy

Jeffrey Alan Hubbell, Melody Swartz, Lambert Charles François Potin, Jun Ishihara

Although a clinical breakthrough for cancer treatment, it remains that a minority of patients respond to checkpoint inhibitor (CPI) immunotherapy. The composition of tumor-infiltrating immune cells has been identified as a key factor influencing CPI therap ...

2019

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Lung cancer

The use of texture-based radiomics CT analysis to predict outcomes in early-stage non-small cell lung cancer treated with stereotactic ablative radiotherapy

Synthetic 3D scaffolds for cancer immunotherapy

MALDI Detection of Exosomes: A Potential Tool for Cancer Studies

Bioengineering human bone marrow models to elucidate the triggers of the stem cell niche

RasGRP1 is a potential biomarker for stratifying anti-EGFR therapy response in colorectal cancer

The antimicrobial peptide defensin cooperates with tumour necrosis factor to drive tumour cell death in Drosophila

Toward Microfluidic Label-Free Isolation and Enumeration of Circulating Tumor Cells from Blood Samples

Adverse effects of immune-checkpoint inhibitors: epidemiology, management and surveillance

A structure-based mechanism of cisplatin resistance mediated by glutathione transferase P1-1

Recruitment of CD103(+) dendritic cells via tumor-targeted chemokine delivery enhances efficacy of checkpoint inhibitor immunotherapy

Graph Chatbot

Chat with Graph Search

Bioengineering human bone marrow models to elucidate the triggers of the stem cell niche

The use of texture-based radiomics CT analysis to predict outcomes in early-stage non-small cell lung cancer treated with stereotactic ablative radiotherapy

Adverse effects of immune-checkpoint inhibitors: epidemiology, management and surveillance

Synthetic 3D scaffolds for cancer immunotherapy

Recruitment of CD103(+) dendritic cells via tumor-targeted chemokine delivery enhances efficacy of checkpoint inhibitor immunotherapy

MALDI Detection of Exosomes: A Potential Tool for Cancer Studies

RasGRP1 is a potential biomarker for stratifying anti-EGFR therapy response in colorectal cancer

Toward Microfluidic Label-Free Isolation and Enumeration of Circulating Tumor Cells from Blood Samples

The antimicrobial peptide defensin cooperates with tumour necrosis factor to drive tumour cell death in Drosophila

A structure-based mechanism of cisplatin resistance mediated by glutathione transferase P1-1