Concept

Amniotic sac

Related publications (25)

Expansion of a VE-Cadherin+CD45+ population in the yolk sac upon Etv2 overexpression in the mouse embryo - Effects of BMP and Wnt signaling inhibition on the differentiation of a Flk1+ extraembryonic mesoderm in vitro model

The difficulty to find compatible donors for bone marrow transplantation makes the need for an alternative source of HSCs urgent. HSC derived from patient-specific iPS cells are ideal candidates for this purpose. Nevertheless, although HSCs are the best ch ...

2011

The Role of Nodal Processing in Pluripotent Progenitors

Anja Dietze

Nodal and its co-receptors of the EGF-CFC family are essential during chordate development, both to maintain pluripotent progenitor cells and to subsequently coordinate their allocation to the different germ layers. How these distinct Nodal activities are ...

EPFL2011

Human fetal bone cells in delivery systems for bone engineering

Dominique Pioletti, Corinne Scaletta, Sandra Jaccoud, Nathalie Hirt-Burri

The aim of this study was to culture human fetal bone cells (dedicated cell banks of fetal bone derived from 14 week gestation femurs) within both hyaluronic acid gel and collagen foam, to compare the biocompatibility of both matrices as potential delivery ...

Wiley-Blackwell2011

StagedSAC: a case study in performance-oriented DSL development

Martin Odersky, Tiark Rompf, Vlad Ureche, Hassan Chafi

Domain-specific languages (DSLs) can bridge the gap between high-level programming and efficient execution. However, implementing compiler tool-chains for performance oriented DSLs requires significant effort. Recent research has produced methodologies and ...

ACM2011

A post-processing pipeline to reconstruct the developing fetal brain using low-resolution MRI

Jean-Philippe Thiran, Meritxell Bach Cuadra, Marie Schaer

Introduction. Development of the fetal brain surface with concomitant gyrification is one of the major maturational processes of the human brain. First delineated by postmortem studies or by ultrasound, MRI has recently become a powerful tool for studying ...

2010

Sutureless ocular surface reconstruction

Basile Salmon

Corneal diseases account for eight million blind people worldwide, making up to 10% of all causes of blindness. As 80% of the information is collected by our senses, blindness is a very invalidating condition which lowers greatly patients’ quality of life. ...

2010

Placental rescue reveals a sole requirement for c-Myc in embryonic erythroblast survival and hematopoietic stem cell function

Armin Ehninger

The c-Myc protein has been implicated in playing a pivotal role in regulating the expression of a large number of genes involved in many aspects of cellular function. Consistent with this view, embryos lacking the c-myc gene exhibit severe developmental de ...

2008

The nodal precursor acting via activin receptors induces mesoderm by maintaining a source of its convertases and BMP4

Luca Pescatore, Felix Naef, Daniel Constam

During early mouse development, the subtilisin-like proprotein convertases (SPC) Furin and PACE4 pattern the primitive ectoderm and visceral endoderm, presumably by activating the TGFss-related Nodal precursor. Here, mutation of the SPC motif provides dire ...

2006

Essential role of endothelial Notch1 in angiogenesis

Freddy Radtke

BACKGROUND: Notch signaling influences binary cell fate decisions in a variety of tissues. The Notch1 receptor is widely expressed during embryogenesis and is essential for embryonic development. Loss of global Notch1 function results in early embryonic le ...

2005

Nodal protein processing and fibroblast growth factor 4 synergize to maintain a trophoblast stem cell microenvironment

Daniel Constam

Before implantation in the uterus, mammalian embryos set aside trophoblast stem cells that are maintained in the extraembryonic ectoderm (ExE) during gastrulation to generate the fetal portion of the placenta. Their proliferation depends on diffusible sign ...

2004

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