Concept

Narcolepsy

Related publications (28)

REM sleep and muscle atonia in brainstem stroke: A quantitative polysomnographic and lesion analysis study

Important brainstem regions are involved in the regulation of rapid eye movement sleep. We hypothesized that brainstem stroke is associated with dysregulated rapid eye movement sleep and related muscle activity. We compared quantitative/qualitative polysom ...

WILEY2022

Theory and application of a data-driven approach to compressive spectrometry in the assessment of neurophotic stimulation

Forrest Simon Webler

Recent advances in biology and neuroscience have elucidated pathways in which visible light initiates a signaling process, via the eye, responsible for activating direct and indirect biological responses. While the full impact of unnatural light patterns ...

EPFL2022

Alertness in work environments - on the role of indoor daylight exposure

Victoria Eugenia Soto Magán

Light enables to see the world around us, while playing a key role in our biological functioning. During the last decades, light has become an important research topic for chronobiologists and neuroscientists, and their findings are increasingly interwoven ...

EPFL2021

Sleep disturbance-related depressive symptom and brain volume reduction in shift-working nurses

Chang-Hyun Park

Disturbed sleep is the most common effect of shift work. A large corpus of research indicates an association between sleep disturbance and depressive symptom in shift workers. In this study, we proposed the mediating role of grey matter (GM) structure in t ...

NATURE PUBLISHING GROUP2020

Molecular codes and in vitro generation of hypocretin and melanin concentrating hormone neurons

Sha Li, Hasan Pezeshgi Modarres, Cyril Mikhail

Hypocretin/orexin (HCRT) and melanin concentrating hormone (MCH) neuropeptides are exclusively produced by the lateral hypothalamus and play important roles in sleep, metabolism, reward, and motivation. Loss of HCRT (ligands or receptors) causes the sleep ...

PNAS2019

Spatial clusters of daytime sleepiness and association with nighttime noise levels in a Swiss general population (GeoHypnoLaus)

Stéphane Joost, Idris Guessous, Rebecca Himsl

INTRODUCTION: Daytime sleepiness is highly prevalent in the general adult population and has been linked to an increased risk of workplace and vehicle accidents, lower professional performance and poorer health. Despite the established relationship between ...

2018

Cortico–reticulo–spinal circuit reorganization enables functional recovery after severe spinal cord contusion

Grégoire Courtine, Bernard Schneider, Quentin Barraud, Léonie Asboth, Mark Andrew Anderson, Lucia Florinda Friedli Wittler, Laetitia Danielle Philippine Baud, Polina Shkorbatova, Janine Beauparlant, Galyna Pidpruzhnykova, Selin Anil, Julie Kreider, Cristina Martinez Gonzalez, Elodie Rey

Severe spinal cord contusions interrupt nearly all brain projections to lumbar circuits producing leg movement. Failure of these projections to reorganize leads to permanent paralysis. Here we modeled these injuries in rodents. A severe contusion abolished ...

2018

Cholinergic, Glutamatergic, and GABAergic Neurons of the Pedunculopontine Tegmental Nucleus Have Distinct Effects on Sleep/Wake Behavior in Mice

The pedunculopontine tegmental (PPT) nucleus has long been implicated in the regulation of cortical activity and behavioral states, including rapid eye-movement (REM) sleep. For example, electrical stimulation of the PPT region during sleep leads to rapid ...

Soc Neuroscience2017

Sleep-dependent consolidation of face recognition and its relationship to REM sleep duration, REM density and Stage 2 sleep spindles

Christian O'Reilly

Face recognition is a highly specialized capability that has implicit and explicit memory components. Studies show that learning tasks with facial components are dependent on rapid eye movement and non-rapid eye movement sleep features, including rapid eye ...

Wiley2017

Cortico-reticulo-spinal circuits mediate functional recovery after spinal cord contusion

Léonie Asboth

After a spinal cord injury (SCI), only half of affected individuals regain voluntary control of leg movements below the level of the lesion. Anatomical, electrophysiological and imaging data revealed that even the most severe forms of SCI usually spare a s ...

EPFL2017

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