Concept

Obstructive sleep apnea

Related publications (56)

Sustained sleep fragmentation affects brain temperature, food intake and glucose tolerance in mice

Pierre Magistretti, Jean-Marie Petit, Maxime Olivier Baud

Sleep fragmentation is present in numerous sleep pathologies and constitutes a major feature of patients with obstructive sleep apnea. A prevalence of metabolic syndrome, diabetes and obesity has been shown to be associated to obstructive sleep apnea. Whil ...

Wiley-Blackwell2013

Integrating non-visual effects of light into lighting simulation: challenges ahead

Marilyne Andersen, María Lovísa Ámundadóttir, Steven W. Lockley

Lighting is a major influential factor that affects human health and sense of wellbeing in the built environment. Since 2002, when the first reports on the discovery of a novel type of photoreceptor were published, a new field of study started to emerge at ...

2013

The effect of continuous positive airway pressure on total cerebral blood flow in healthy awake volunteers

Nikolaos Stergiopoulos, Bryn Andrew Martin

Continuous positive airway pressure (CPAP) is the gold standard treatment for obstructive sleep apnea. However, the physiologic impact of CPAP on cerebral blood flow (CBF) is not well established. Ultrasound can be used to estimate CBF, but there is no wid ...

Springer-Verlag2013

Principal component structuring of the Non-REM sleep EEG spectrum in older adults yields age-related changes in the sleep and wake drives

Mirjam Münch

Age-related disturbances of the sleep-wake cycle can reflect ontogenetic changes in regulatory mechanisms underlying normal and pathological aging, but the exact nature of these changes remains unclear. The present report is the first attempt to apply prin ...

2013

Evidence that the Lunar Cycle Influences Human Sleep

Endogenous rhythms of circalunar periodicity (similar to 29.5 days) and their underlying molecular and genetic basis have been demonstrated in a number of marine species [1, 2]. In contrast, there is a great deal of folklore but no consistent association o ...

Elsevier2013

Challenging the sleep homeostat: Sleep in depression is not premature aging

Mirjam Münch

Objectives: The close relationship between major depression and sleep disturbances led to the hypothesis of a deficiency in homeostatic sleep pressure in depression (S-deficiency hypothesis). Many observed changes of sleep characteristics in depression are ...

Elsevier2012

Effects of prior light exposure on early evening performance, subjective sleepiness, and hormonal secretion

Jean-Louis Scartezzini, Mirjam Münch, Friedrich Linhart, Apiparn Borisuit

In sighted humans, light intensity, timing, exposure duration, and spectral composition of light are important to entrain the endogenous circadian pacemaker to the 24-h day-night cycle. We tested the impact of two realistic office lighting conditions durin ...

American Psychological Association2012

Electrical impedance tomography system based on active electrodes

Peter Seitz

Electrical impedance tomography (EIT) can image the distribution of ventilated lung tissue, and is thus a promising technology to help monitor patient breathing to help selection of mechanical ventilation parameters. Two key difficulties in EIT instrumenta ...

Institute of Physics2012

Light and chronobiology: Implications for health and disease

Mirjam Münch

Environmental light synchronizes the primary mammalian biological clock in the suprachiasmatic nuclei, as well as many peripheral clocks in tissues and cells, to the solar 24-hour day. Light is the strongest synchronizing agent (zeitgeber) for the circadia ...

Les Laboratories Servier2012

The Impact of Sleep Fragmentation on Sleep Homeostasis, Brain and Peripheral Energy Metabolism and Spatial Learning

Maxime Olivier Baud

The quality of sleep has recently come to the forefront of public health concerns in industrialized nations. Indeed, voluntary sleep curtailment is widespread, sleep disorders are increasingly recognized and both correlate with the current epidemiology of ...

EPFL2011

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