Concept

Octopamine

Related publications (23)

Powering the social brain: Mitochondria in social behaviour

Maria del Carmen Sandi Perez, Dogukan Hazar Ülgen, Silvie Rosalie Ruigrok

A central role of brain mitochondria in regulating and influencing social behaviour is emerging. In addition to its important roles as the "powerhouses" of the cell, mitochondria possess a plethora of cellular functions, such as regulating ion homeostasis, ...

2023

Ageing and reinforcement learning

Michael Herzog, Wei-Hsiang Lin

Learning to achieve one’s goal in a complex environment is a complicated task. In reinforcement learning (RL) tasks, an agent interacts with the environment to learn optimal actions. In humans, striatal areas are strongly involved in these tasks. During ag ...

2021

A Manganese Phosphate Nanocluster Activates the cGAS‐STING Pathway for Enhanced Cancer Immunotherapy

Li Tang, Yugang Guo, Yuqing Xie, Min Gao, Armand Kurum, Kewen Lei, Yu Zhao, Xiaomeng Hu, Simon Bart M. Van Herck

Targeting the stimulator of interferon genes (STING) pathway with cyclic dinucleotides (CDNs), the natural STING agonists, is a promising immunotherapeutic strategy for cancer. However, the clinical application of natural CDNs as therapeutics is greatly hi ...

2021

Octopamine neuron dependent aggression requires dVGLUT from dual-transmitting neurons

Brian Donal McCabe

Neuromodulators such as monoamines are often expressed in neurons that also release at least one fast-acting neurotransmitter. The release of a combination of transmitters provides both "classical" and "modulatory" signals that could produce diverse and/or ...

2020

Risk prediction error signaling: A two-component response?

Michael Herzog, Ophélie Gladys Favrod, Kerstin Preuschoff, Marc Michael Lauffs, Sophie Alberta Catherine Geoghan

Organisms use rewards to navigate and adapt to (uncertain) environments. Error-based learning about rewards issupported by the dopaminergic system, which is thought to signal reward prediction errors to make adjustmentsto past predictions. More recently, t ...

2020

Neurobiological links between stress and anxiety

Maria del Carmen Sandi Perez

Stress and anxiety have intertwined behavioral and neural underpinnings. These commonalities are critical for understanding each state, as well as their mutual interactions. Grasping the mechanisms underlying this bidirectional relationship will have major ...

2019

Differentiating Siblings: The Case of Dopamine and Norepinephrine

Nako Nakatsuka

Monitoring dopamine and norepinephrine (or other structurally similar neurotransmitters) in the same brain region necessitates selective sensing. In this Viewpoint, we highlight electrochemical and optical strategies for advancing simultaneous real-time me ...

2017

dHb9 Expressing Larval Motor Neurons Persist Through Metamorphosis to Innervate Adult-Specific Muscle Targets and Function in Drosophila Eclosion

Soumya Banerjee

The Drosophila larval nervous system is radically restructured during metamorphosis to produce adult specific neural circuits and behaviors. Genesis of new neurons, death of larval neurons and remodeling of those neurons that persistent collectively act to ...

Wiley-Blackwell2016

Spatiotemporal neuromodulation therapies engaging muscle synergies improve motor control after spinal cord injury

Silvestro Micera, Stéphanie Lacour, Grégoire Courtine, Jocelyne Bloch, Eduardo Martin Moraud, Quentin Barraud, Léonie Asboth, Marco Capogrosso, Pavel Musienko, Rubia van den Brand, Ivan Rusev Minev, Nikolaus Wenger, Jérôme Gandar, Arthur Edouard Hirsch, Laetitia Danielle Philippine Baud, Natalia Pavlova, Simone Ellen Joze Duis, Julie Kreider, Andrea Mortera

Electrical neuromodulation of lumbar segments improves motor control after spinal cord injury in animal models and humans. However, the physiological principles underlying the effect of this intervention remain poorly understood, which has limited the ther ...

Nature Publishing Group2016

Modeling Resting-State Functional Networks When the Cortex Falls Asleep: Local and Global Changes

Patric Hagmann

The transition from wakefulness to sleep represents the most conspicuous change in behavior and the level of consciousness occurring in the healthy brain. It is accompanied by similarly conspicuous changes in neural dynamics, traditionally exemplified by t ...

Oxford University Press2014

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