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A microelectrode array (MEA) consisting of 34 silicon nitride passivated Pt-tip microelectrodes embedded on a perforated silicon substrate (porosity 35%) has been realized. The electrodes are 47 μm high, of which only the top 15 μm are exposed Pt-tips havi ...
Rat spinal networks generate a spontaneous rhythmic output directed to motoneurons under conditions of increased excitation or of disinhibition. It is not known whether these differently induced rhythms are produced by a common rhythm generator. To investi ...
Locomotion in vertebrates is controlled by central pattern generators in the spinal cord. The roles of specific network architecture and neuronal properties in rhythm generation by such spinal networks are not fully understood. We have used multisite recor ...
A thin aqueous layer is formed between the polymeric ion-selective membrane and an inner gold electrode. Its composition can be altered upon sample changes, which leads to drifting potentials. It is shown by theory and experiment that interfering ions ente ...
The fabrication, characterization and application of polyimide-based flexible microelectrodes for recording from and stimulation of biological tissue are described. The planar electrodes consist of a polyimide-platinum-polyimide sandwich structure with a t ...
A simple and efficient technique for the fabrication of buried microfluidic channels is presented. Microchannels made using a contribution of thick liquid and laminated photopolymers are used for the realization of smart microchips for culture, stimulation ...
A three-dimensional platinum (Pt) microelectrode array embedded on a micromachined silicon (S) substrate (porosity of 13%, via hole diameter of 40 μm) has been developed. Electrodes are 35-μm wide and 20-μm high, spaced 200 μm apart and arranged in an elli ...
A theoretical approach to the steady-state limiting current response behavior of multiple microelectrode arrays, consisting of spherical, hemispherical, disk-shaped, or hemicylindrical electrode units, is presented. An approximative treatment is given for ...
Fetal or early postnatal brain tissue can be cultured in viable and healthy condition for several weeks with development and preservation of the basic cellular and connective organization as so-called organotypic brain slice cultures. Here we demonstrate a ...
A theoretical approach to the current vs. time behavior of arrays of hemispherical or disc-shaped microelectrodes is presented. The treatment includes the chronoamperometric response to changes of the applied potential, and the dynamic response to changes ...
