Concept

Microelectrode array

Related publications (283)

Generalized integrate-and-fire models of neuronal activity approximate spike trains of a detailed model to a high degree of accuracy

We demonstrate that single-variable integrate-and-fire models can quantitatively capture the dynamics of a physiologically-detailed model for fast-spiking cortical neurons. Through a systematic set of approximations, we reduce the conductance based model t ...

American Physiological Society2004

Spiking neural network device

Dario Floreano

Device comprising storage means (51) for storing a genotypic representation (3) of a spiking neural network comprising spiking neurons (1) and input neurons (2) connected by synapses, and computer program portions for performing the steps of mutating said ...

2004

The Spike Response Model: A Framework to Predict Neuronal Spike Trains

Wulfram Gerstner, Renaud Jolivet

We propose a simple method to map a generic threshold model, namely the Spike Response Model, to artificial data of neuronal activity using a minimal amount of a priori information. Here, data are generated by a detailed mathematical model of neuronal acti ...

Springer-Verlag2003

Studying Phase Synchrony for Classification of Mental Tasks in Brain Machine Interfaces

José del Rocio Millán Ruiz, Silvia Chiappa

Electroencephalogram recordings during imagination of mental tasks allow for developing a new communication device for, e.g., motor disabled people. 32-channel EEG was recorded from 5 healthy subjects while performing, after instruction and in random order ...

2003

A three-dimensional multi-electrode array for multi-site stimulation and recording in acute brain slices

Philippe Renaud, Marc Olivier Heuschkel

Several multi-electrode array devices integrating planar metal electrodes were designed in the past 30 years for extracellular stimulation and recording from cultured neuronal cells and organotypic brain slices. However, these devices are not well suited f ...

2002

Biosystem for the culture and electrical characterisation of epithelial cell tissues

Serge Hediger

The aim of this work was to develop a microchamber system for performing electrophysiological measurements on epithelial surface on culture membranes in the mm2 range. This miniaturised system permits the use of small quantities of epithelial cells, which ...

EPFL2002

Electrical properties of light-addressed sub-µm electrodes fabricated by use of nanostencil-technology

Jürgen Brugger

A wide range of applications in neurotechnological research rely on planar microelectrode arrays (MEA) but the disadvantage of these systems is the low density of electrodes caused by the problem of wiring a great number of electrodes. In turn this results ...

2002

Microelectrodes with three-dimensional structures for improved neural interfacing

Philippe Renaud, Marc Olivier Heuschkel, Stefan Metz, Raphael Holzer

This paper describes the development of microelectrodes with integrated three-dimensional electrode structures. The integration of three-dimensional structures aims at an improvement of the electrode/tissue interface. Due to the increase in surface area th ...

2001

Biocompatibility of Si-based arrays of electrodes coupled to organotypic hippocampal brain slice cultures

In this study we examined the passive biocompatibility of a three-dimensional microelectrode array (MEA), designed to be coupled to organotypic brain slice cultures for multisite recording of electrophysiological signals. Hippocampal (and corticostriatal) ...

2001

Fabrication of flexible, implantable microelectrodes with embedded fluidic microchannels

Philippe Renaud, Stefan Metz, Raphael Holzer

This paper describes the fabrication of polyimide-based microelectrodes with embedded fluidic microchannels. The thin-film structures combine for the first time a fluidic system with microelectrodes for recording and stimulation of biological signals on a ...

2001

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