Concept
Microelectrode array
Related publications (283)
Stability of flexible thin-film metallization stimulation electrodes: analysis of explants after first-in-human study and improvement ofin vivoperformance
Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini
Objective.Micro-fabricated neural interfaces based on polyimide (PI) are achieving increasing importance in translational research. The ability to produce well-defined micro-structures with properties that include chemical inertness, mechanical flexibility ...
2020Human Cochlear Nucleus on 7 Tesla Diffusion Tensor Imaging: Insights Into Micro-anatomy and Function for Auditory Brainstem Implant Surgery
Objective:The cochlear nucleus (CN) is the target of the auditory brainstem implant (ABI). Most ABI candidates have Neurofibromatosis Type 2 (NF2) and distorted brainstem anatomy from bilateral vestibular schwannomas. The CN is difficult to characterize as ...
LIPPINCOTT WILLIAMS & WILKINS2020Axon morphology is modulated by the local environment and impacts the noninvasive investigation of its structure-function relationship
Jean-Philippe Thiran, Tim Bjørn Dyrby
Axonal conduction velocity, which ensures efficient function of the brain network, is related to axon diameter. Noninvasive, in vivo axon diameter estimates can be made with diffusion magnetic resonance imaging, but the technique requires three-dimensional ...
NATL ACAD SCIENCES2020Nanovolcano microelectrode arrays: toward long-term on-demand registration of transmembrane action potentials by controlled electroporation
Philippe Renaud, Arnaud Bertsch, Benoît Xavier Emmanuel Desbiolles, Nicolas Grégoire Maïno, Stephan Rohr, Etienne de Coulon
Volcano-shaped microelectrodes (nanovolcanoes) functionalized with nanopatterned self-assembled monolayers have recently been demonstrated to report cardiomyocyte action potentials after gaining spontaneous intracellular access. These nanovolcanoes exhibit ...
2020First Biopotential Recordings from a Liquid Crystal Optrode
One of the goals of the Neural Engineering System Design (NESD) program in the United States and of similar programs around the world is to develop an interface able to read from one million neurons in parallel. This is well beyond the capabilities of trad ...
SPIE-INT SOC OPTICAL ENGINEERING2019Inferring and validating mechanistic models of neural microcircuits based on spike-train data
The interpretation of neuronal spike train recordings often relies on abstract statistical models that allow for principled parameter estimation and model selection but provide only limited insights into underlying microcircuits. In contrast, mechanistic m ...
2019