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Située au sud des Alpes, Lugano se caractérise par une forte densité urbaine, fruit du développement spéculatif de plusieurs décennies. Un réseau compact de palazzine, disposé selon une grille orthogonale, s'étend sur une grande partie du territoire et ent ...
The cell is a complex system involving numerous components, which may often interact in a non-linear dynamic manner. Diseases at the cellular level are thus likely to involve multiple cellular constituents and pathways. As some drugs, or drug combinations, ...
S-palmitoylation involves the attachment of a 16-carbon long fatty acid chain to the cysteine residues of proteins. The process is enzymatic and dynamic with DHHC enzymes mediating palmitoylation and acyl-protein thioesterases reverting the reaction. Prote ...
Extra-cellular matrix (ECM) tethered morphogen gradients play an important role in tissue development and regeneration. There is currently only a limited set of model systems which can mimic these gradients in an artificial ECM-like environment. We have de ...
The Chemical and Biological Microsystems Society2008
Compléter la périphérie d'un îlot, aménager un jardin public à l'intérieur, combler les niches à l'intérieur de l'îlot, percer un passage public au lieu de la cité. ...
En vieille ville de Barcelone et face à quelques édifices autonomes, il s'agit d'insérer un important bâtiment universitaire dans ce tissu dense et complexe. Un premier volume complète l'îlot en proposant, devant lui, une rue élargie (voire une place allon ...
