Concept

Human tooth development

Related publications (35)

Surface Modification of Biomaterials for Conjugation with Human Fetal Osteoblasts

Sandrine Gerber, Françoise Borcard, Céline Marie Anne Journot, Phally Kong

Surface functionalization of hydroxyapatite (HA) and β-tricalcium phosphate (TCP) bioceramics with chemical ligands containing a pyrrogallol moiety was developed to improve the adhesion of bone cell precursors to the biomaterials. Fast and biocompatible co ...

Swiss Chemical Soc2013

Patterning and shaping the endoderm in vivo and in culture

Marine Marie Kraus, Anne Grapin-Botton

The definitive endoderm (DE) was first defined as the innermost germ layer found in all metazoan embryos. During development, it gives rise to a vast array of specialized epithelial cell types lining the respiratory and digestive systems, and contributes t ...

Elsevier2012

Functionalization of microstructured open-porous bio-ceramic scaffolds with human fetal cells

Sandrine Gerber, Corinne Scaletta, Françoise Borcard

Bone substitute materials allowing trans-scaffold migration and in-scaffold survival of human bone-derived cells are mandatory for development of cell-engineered permanent implants to repair bone defects. In this study, we evaluated the influence on human ...

American Chemical Society2012

Immobilizing device for a toothed wheel

Simon Nessim Henein, Fabiano Colpo

The invention relates to an immobilizing device for a toothed wheel suitable for the field of horology where it can be part of a direct- or indirect-impulse escapement, in particular in a wristwatch. This immobilizing device (1, 2, 3, 4, 5, 6) comprises: — ...

European Patent Office2011

Covalent cell surface functionalization of human fetal osteoblasts for tissue engineering

Sandrine Gerber, Corinne Scaletta, Davide Städler, Aurélien Godinat, Françoise Borcard

The chemical functionalization of cell-surface proteins of human primary fetal bone cells with hydrophilic bioorthogonal intermediates was investigated. Toward this goal, chemical pathways were developed for click reaction-mediated coupling of alkyne deriv ...

2011

Epiprofin/Sp6: A new player in the regulation of tooth development

Lucia Jimenez Rojo

Odontogenesis is governed by a complex network of intercellular signaling events between the dental epithelium and mesenchyme. This network leads to the progressive determination of tooth shape, and to the differentiation of these tissues into enamel-produ ...

2010

Three-dimensional morphometry of strained bovine periodontal ligament using synchrotron radiation-based tomography

John Botsis, Joël Cugnoni, Marzio Bergomi, Marco Stampanoni, Philipp Schneider

The periodontal ligament (PDL) is a highly vascularized soft connective tissue. Previous studies suggest that the viscous component of the mechanical response may be explained by the deformation-induced collapse and expansion of internal voids (i.e. chiefl ...

2010

The grinding tip of the sea urchin tooth exhibits exquisite control over calcite crystal orientation and Mg distribution

Anders Meibom

The sea urchin tooth is a remarkable grinding tool. Even though the tooth is composed almost entirely of calcite, it is used to grind holes into a rocky substrate itself often composed of calcite. Here, we use 3 complementary high-resolution tools to probe ...

2009

Mechanical response of periodontal ligament: Effects of specimen geometry, preconditioning cycles and time lapse

John Botsis, Marzio Bergomi

This study was conducted as part of research line addressing the mechanical response of periodontal ligament (PDL) to tensile-compressive sinusoidal loading The aim of the present project was to determine the effect of three potential sources of variabilit ...

2009

Experimental and numerical investigations on the fluid contribution to the tensile-compressive mechanical behavior of the bovine periodontal ligament

Marzio Bergomi

Orthodontic treatments are all based on the experimental evidence that teeth can be forced to move in the dental arch by means of applied mechanical forces. Since it allows for prediction of dental mobility, the mechanical characterization of the tissues i ...

EPFL2008

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